DL: Renal Case Studies (3 Cases)

Question 1

How would a bleed into the gut present clin path?

Answer 1

^^^ urea > ^ creatinine

v protein

Question 2

What normal variation does PCV TP show?

Answer 2

Young dogs ^PCV v TP

Old dogs vPCV ^ TP

Question 3

Tx congenital renal dysplasia?

Answer 3

No tx (lack of kidney tissue) PTS

Question 4

What is hypercalcaemia of ,malignancy most commonly seen with?

Answer 4

• lymphosarcoma

- anal sac carnicoma

Question 5

Define hyposthenuria, isisthenuria and hypersthenuria. When are these appropriate?

Answer 5

Hyposthenuria

• anything is appropriate unless azotaemic*
• if azotaemic should be >1.035

Question 6

What tx should lymphoid malignancy respond to a single shot of (not necessarily cure but see response)

Answer 6

L-asparaginase

Question 7

What does a low Ph with ^ Ca allow you to r/o

Answer 7

Structural kidney disease ( expect ^Ph)

Question 8

Are animals sick with 1* hyperPT?

Answer 8

NO

Question 9

Does hyper Ca cause depressed, tucked up appearance?

Answer 9

NO

Question 10

What can large bowel D+ be refined into?

Answer 10

1* casues

- 2* VERY RARE large bowel

Question 11

What type of pathology does meleana alone suggest?

Answer 11

1* GIT

- 1* and 2* expect other signs

Question 12

What shoudl the Ca P product be?

Question 13

Px Vit D toxicity

Answer 13

Not 100% sucess rate with tx

Question 14

What can altered gut motility predispose to?

Answer 14

Intussecption

Question 15

Can acidosis be dx by urine?

Answer 15

No

Question 16

Causes acidosis

Answer 16

• urea and byproducts acidic

- anaemia -> anaerobic respiration -> acidifying

Question 17

Should serum PTH be normal with ^ Ca?

Answer 17

NO should be low belwo ref range

Question 18

What is the desmopressin response test used for? Is this reliable?

Answer 18

• central v nephrogenic DI
• can be positive even with 1* PD so always water deprive first
• can take a long time before dehydration sets in

Question 19

How soon after administration should you see a response with desmopressin?

Answer 19

2-12hrs

Question 20

Tx central DI? Cost?

Answer 20

Desmpressin eye drops ~ £25/month

Question 21

Is the water deprivation test a safe test?

Answer 21

Risky

• if do have central DI will dehydrate very rapidly
• can die overnight
• must lose 5% BW to prove dehydration (or measure TP/PCV/Na/urea etc.)

Question 22

How can hyperadrenocorticism be ruled out in some patients before doing any work up?

Answer 22

If they have pruritis cannot be HAC as would tx their own skin condition!