Diversity of Cells and Their Function Flashcards
How are specimens prepared for light and electron microscopy?
Tissue is ‘fixed’ with a chemical like formalin
Tissue is thinly sliced
Tissue is impregnated with support material (usually wax) by dehydrating, putting into organic solvent and placing in hot wax
Thin sections cut on a microtome and put onto microscope slides, wax washed out, tissue rehydrated
Tissue stained
What are artifacts?
Changes from the original tissue
What does H&E mean?
An abbreviation of Haematoxylin and Eosin, the most common combination of stains
What are the four basic tissue types?
Epithelial
Connective
Muscle
Nervous
What do epithelial cells do?
Line surfaces of body or hollow organs
Form glands
What is connective tissue?
Forms the framework of the body
Has a role in development, growth and homeostasis of tissues and energy storage
What is muscle tissue?
Cells that are specialised to generate force by contracting - movement
What does nervous tissue consist of?
Neurons and their supporting cells
What is the function of nervous tissue?
Control
Communication between different parts of the body
Why are epithelial cells good for covering the surfaces of the body?
Adhesion between them is strong so they form sheets of cells
What is a basal lamina?
The layer of extracellular matrix components to which epithelial cells are attached to at their bottom surface
Do epithelial cells have blood vessels supplying them?
No - non-vascular
Are epithelial cells polarised?
Yes
What are the functions of epithelia?
Mechanical and chemical barrier Absorption Secretion Containment Locomotion
What are the different shapes epithelial cells can be?
Squamous (fried egg)
Cuboidal
Columnar
What are the names for the different number of layers epithelial cells can have?
1 - simple
2 or more - stratified
Appears to have multiple but actually just one - pseudostratified
What is the term for the presence of specialised cell types in epithelia?
Goblet cells
What are the surface specialisation of epithelia?
Prominent microvilli
Cilia
Presence of layers of keratin proteins
What is the function of glandular epithelia?
Produce secretions
Where is the product secreted by endocrine glands?
Towards the basal end of the cell then distributed throughout the body
Where is the product secreted by exocrine glands?
Towards the apical end of the cell into the lumen of an internal space, a duct, or onto the body surface
What are the three types of connective tissue?
Soft connective tissue
Hard connective tissue
Blood and lymph
What does connective tissue consist of?
Extracellular matrix
Cells
What determines the type of connective tissue?
The types and relative amounts of extracellular matrix and cells