Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Renal 2 Quiz 1 > Diuretics > Flashcards

Diuretics Flashcards

1
Q

Thiazide diuretics include

A

Hydrochlorothiazide
Metolazide
Chloralidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Indications for thiazide diuretics

A

Hypertension

Edema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Loop diuretics include

A

Furosemide
Torsemide
Bumetanide
Ethacrynic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Indications for loop diuretics

A

Edema

Hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

K sparing diuretics

A

Na channel blockers - amiloride and triaterene

Aldosterone antagonists - spironolactone and eplerenone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Indications for k sparing drugs

A

Edema and hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Aquaretics

A

Conivaptan

Tolvaptan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Indications for aquareteicis

A

Hyponatremia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Carbonic anyhydrase inhibitors

A

Acetazolamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Indications for ca inhibitors

A

Urinary alkalinzation
Mountain sickness
Glaucoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Osmotic diuretics

A

Mannitol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

K sparing diuretics

A

Na channel blockers - triamterene, amiloride

Aldosterone antagonists - spironolactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

K wasting diuretics

A

Thiazides (Na Cl blockers)
Loop diuretics (nkcc cotransporter)
Carbonic anhydrase inhibitors
Osmotic diuretics (nonresorbable solutes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Mechanism of action of loop diuretics

A

Block na k 2cl cotransporter in TAL

Potassium diffuses into lumen and blocks Ca and Mg pericellular tranport

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

At maximum doses, what does furosemide do

A

Max doses - dissipation of medullary interstitial gradient IRRESPECTIVE of whether urine was dilute or concentrate
ISOTONIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Indications for loop diuretics

A

Rapid and massive fluid removal
Edema, hepatic, cardiac or renal origin
Acute pulmonary edema 0 removes excess extracellular fluid
Hypertension that is unresponsive to other diuretics
Works when RBF and GFR are low

17
Q

AE of loop diureticds

A 
Hyponatremia 
Hypochloremia
Hypokalemia - k wasting diuretic 
Hypocalcemia
Hypotension 
Hypomagnesium 
OTOTOXICITY 
Hyperglycemia, hyperurecemia 
Hyperlipdemia 
Crosses placenta
18
Q

Why do k wasting diuretics cause hypokalemia

A

Na not reabsorbed in talh is partially reabsorbed by downstream na cl cotransporter via na k exchange in collection
K/H exchange at cells to try to maintain plasma k —> hypochloremic metabolic alkalosis

19
Q

Drug interactions with loop diuretics

A

Digoxin
Ototoxic drugs
Potassium sparing diuretics

20
Q

MoA of thiazide diuretics

A

Block NaCl cotransporter in DCT

SEVERE magnesium wasting

21
Q

Thiazides are used in the tx of what type of diabetes insidious

A

Nephrogenic

22
Q

Main uses of thiazides

A

Primary hypertension and edema
Nephrogenic diabetes insipidus
Decreases Ca excretion - can decrease risk of kidney stones

23
Q

AE of thiazides

A 
Hypokalemia
 K sparing diuretic
Hypochloremic metabolic alkalosis
Hypomagnesia 
Increases plasma glucose, urate, lipid 
Avoid in pregnancy

Renal 2 Quiz 1 (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions