Diuretics Flashcards
Thiazide Adverse Effects
Hyperglycemia
Hypokalemia
Elevates triglycerides and LDL
Elevates uric acid
Allergic to Thiazide
Avoid self drugs
Benefits of Thiazide
decrease calcium excretion by the kidney
stimulate osteoclast formation
Potassium-Sparing Diuretics “Black Box Warning”
Hyperkalemias
Increased risk with renal impairment, diabetes, elderly, severely ill
Potassium-Sparing Diuretics
No potassium supplement
Avoid salt substitutes that contain potassium
Avoid with severe renal disease (increase risk of hyperkalemia)
combination of ACEI/ARBs (increase risk of hyperkalemia)
Loop diuretics Adverse Effect
Electrolytes (hypokalemia, hyponatremia, Low chlorine)
Hypovolemia, hypotension
Pancreatitis, jaundice, rash
Ototoxicity
Aldosterone Antagonists Adverse Effects
Galactorrhea
Hyperkalemia
Aldosterone Antagonists
Black Box Warning
Increase risk for benign
malignant tumors