Diuretics Flashcards
Conditions causing edema? (3)
1) altered blood circulation (↑ art/ven pressure)
2) altered blood composition (↓ gradient, Na+/H2O retention)
3) inadequate lymph drain
Which diuretics affect K+ reab/secretion?
Reab in PCT: Φ effect
Secrete in DCT: Aldo-Antag and K+-sparing
Which diuretics affect Ca2+/Mg reab/EXcretion?
Ca2+ reab: thiazide
Ca2+/Mg excr: loop
HypoK+ Metabolic Alkalosis causes?
K+/H+ loss at Na+ exchange sites
Plasma vol contracts -> stim aldo secretion -> more K+ loss
Combo of thiazide/loop may do what?
cause diuresis when neither worked alone
Combo of K+-sparing/loop or thiazide may do what?
balance K+ loss
Order of maxi diuretic effects?
loop»_space; thiazide»_space; CA inhib > K+-spare
Ca2+ inhb only last few days