Diure Flashcards

1
Q

Inhiben la reabsorción renal de agua y electrolitos

Disminuyen la volemia

A

No mejoran supervivencia IC

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2
Q

Tiazidas
Clortalidona
Hidroclorotiazida

A

Inhiben la reabsorción de Na y Cl en el t contorneado DISTAL y en la porción cortical ascendente del ASA de HENLE bloqueando los canales de Cl

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3
Q

Uso tiazidas

A
HTA 
IC
diabetes insípida 
Hipercalciuria
Litiasis calcica recidivante
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4
Q

D asa
Furosemida
Bumetanida

A

Más potentes

Inhiben la reabsorción Na K y Cl ASA ASCENDENTE DE HENLE bloqueo cotransporte

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5
Q

D ASA

Efecto

A

Disminución osmolaridad en el instersticio medular

  • vasodilatación venosa
  • disminución de la precarga
  • desviación flujo renal a la corteza (aumento del flujo plasmarico renal)
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6
Q

D ASA USO

A

Ic casos refractarios y edema agudo de pulmon
Hta IRC
ascitis
Sx nefrotico

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7
Q

D ahorradores de K

Antagonistas de los receptores de mineralocorticoides

A

Espironolactona

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8
Q

D ahorradores de k

Inhibidores directos del transporte de Na

A

Amilorida fibrosis quistica
Triamtereno

Sx de Liddle

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9
Q

Espironolactona

A

Antagonista receptor nuclear aldosterona t COLECTOR
Teanscripcion: tarda horas en hacer efecto completo
Elimina Na
Reabsorbe K y H

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10
Q

Espironolactona

Efecto adverso

A

Ginecomastia dolorosa

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11
Q

Uso

Espironolactona

A

Ascitis cirrotico
Sx de Bartter
Hiperaldosteronismo primario
IC SISTOLICA DE MALA CLASE FUNCIONAL (no x diurético)

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12
Q

D Osmoticos

Se filtran y no se reabsorben pérdida de agua y electrolitos

A

Sx desequilibrio dialitico
Glaucoma de ángulo cerrado
Edema cerebral

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13
Q

Interacción

A

Sulfoniluras

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