Distribution lecture Flashcards
1
Q
Albumin
A
main function is to maintain oncotic pressure of blood
most abundant plasma protein
Serum levels are decreased in liver and kidney diseases
2
Q
a1- acid glycoprotein
A
also known as orosomucoid
Produced in the liver
Binds primarily weakly basic (cationic) drugs
such as tertiary and quaternary amines
Serum levels increased during acute phase
reaction, e.g., inflammation and burns
Serum levels are decreased in liver and kidney diseases
3
Q
Lipoproteins
A
contains LDL and HDL
binds hydrophobic drugs
Altered in some disease states, including heart disease
