Disorders of the Blood and Lymphatic Systems Flashcards
anemia that results from impairment or failure of bone marrow
aplastic anemia
common form of megaloblastic anemia that is caused by the malabsorption of vitamin B12 owing to a lack of intrinsic factor (IF) produced in the glands of the gastric mucosa
pernicious anemia
most common genetic disorder in the world
thalassemia
occurs frequently in people from Mediterranean countries, most common
thalassemia beta
deficit or abnormality of clotting factor VIII and is the most common inherited clotting disorder
hemophilia A/classic hemophilia
involves a deficit of factor IX
hemophilia B/Christmas disease
results from decrease in factor XI
hemophilia C/Rosenthal’s hemophilia
disorder that involves excessive bleeding and excessive clotting
Disseminated intravascular coagulation (DIC)
a group of inherited or acquired disorders that increase the risk of developing abnormal clots int he veins or arteries
thrombophilia
condition in which there is an increased production of erythrocytes, granulocytes, and thrombocytes resulting in increased blood volume and viscosity
primary polycythemia/polycythemia vera
neoplastic disorders involving the white blood cells
leukemia
3 functions of blood through the body
- transport oxygen and nutrients to all tissues.
- remove waste products of cellular metabolism.
- play a critical role in the body’s defenses/immune system, and serve in maintaining body homeostasis.
two types of circulation
pulmonary circulation and systemic circulation
smaller branches of arteries that control the amount of blood flowing into capillaries
arterioles
very small vessels organized in numerous networks that form the microcirculation
capillaries
where is most of the blood during circulation?
veins, 70%
another name for veins
capacitance vessels
three layers of walls of arteries and veins
tunica intima, tunica media, tunica adventitia
inner layer of veins and arteries
tunica intima
layer of smooth muscle that controls the diameter and lumen size of the blood vessel, middle layer
tunica media
outer connective tissue later that contains elastic and collagen fibers
tunica adventitia
tiny blood vessels that supply blood to the tissues of the walls itself
vasa vasorum
reflex adjustment in a small area of a tissue or an organ, varies depending on the needs of the cells in the area
auto regulation