Disorders Of Malabsortion

Question 1

Etiology for malabsorption……..? Malabsorption can result from a defect in the nutrient digestion in the intestinal lumen or from defective mucosal absorption.

Answer 1

Malabsorption can result from a defect in the nutrient digestion in the intestinal lumen or from defective mucosal absorption.

Question 2

The common presenting features, especially in toddlers with malabsorption……..?

Answer 2

Diarrhea, abdominal distention, and failure to gain weight, with a fall in growth chart percentiles

Physical findings include abdominal distention, muscle wasting, and the disappearance of the subcutaneous fat, with subsequent loose skinfolds

Question 3

In secretory diarrhea caused by disorders such as congenital chloride diarrhea (CCD) and microvillus inclusion disease (MVID) the stool characteristics……

Answer 3

The stool is watery and voluminous and can be mistaken for urine

Question 4

The nature of the diarrhea in carbohydrate malabsorption……..?

Answer 4

Explosive watery diarrhoea

Question 5

The nature of diarrhoea in celiac disease……?

Answer 5

loose, bulky stools

Question 6

Pasty and yellowish offensive stools suggest …….?

Answer 6

Exocrine pancreatic insufficiency

Question 7

The most common cause of exocrine pancreatic insufficiency in children

Answer 7

Cystic fibrosis

Question 8

What is fecal elastase-1 estimation…..?

Answer 8

Fecal elastase-1 estimation is a sensitive test to assess exocrine pancreatic function in chronic cystic fibrosis and pancreatitis.

Elastase-1 is a stable endoprotease unaffected by exogenous pancreatic enzymes.

One disadvantage of the fecal elastase-1 test is the lack of full differentiation between primary exocrine pancreatic insufficiency and exocrine pancreatic dysfunction secondary to intestinal villous atrophy.