disorders of ion channels

Question 1

Channelopathies

Answer 1

disturbed function of ion channels

Question 2

Hypokalemic peirodic paralysis

Answer 2

• mutation in muscle voltage gated calcium channel
• Very low potassium levels
• muscle weakness / paralysis

Question 3

Hyperkalemic periodic paralysis

Answer 3

• higher than normal potassium level in the blood

- muscle weakness

Question 4

Limbic encephalitis

Answer 4

• autoimmune disease
• brain inflammation as a result of body producing antibodies against itself
• limbic areas of the brain are inflamed

Question 5

Myasthenia gravis

Answer 5

• Autoimmune
• antibodies bind to post synaptic acetyl choline receptors and thus impair neuromuscular transmission
• Fatigueable muscle weakness
• Affects eye and occular muscles