Disorders of hemostasis

Question 1

Results in undesirable clot formation

Answer 1

Thromboembolic disorder

Question 2

Abnormalities that prevent normal clot formation

Answer 2

bleeding disorder

Question 3

Involves both Thromboembolic and bleeding disorders

Answer 3

Disseminated intravasular coagulation

Question 4

Thromboembolic conditions:
Thrombi and ()
DVT is ()
-Thrombus: clot still attached to vessel, may block circulation
-(): thrombus freely floating in bloodstream
-(): embolus obstructing a vessel
Risk factors: atherosclerosis, inflammation, slowly flowing blood

Answer 4

emboli
Deep vein Thrombosis
Embolus
Embolism

Question 5

() drugs used to prevent undesirable clotting
-(): antiprostaglandin that inhibits thromboxane A2, lowers HR
(): for pre and postoperative cardiac care
(): and direct oral anticoagulants: reduce risk of stroke, interfers with vitamin ()

Answer 5

Anticoagulant
Aspirin
Heparin
Warfarin
K

Question 6

Bleeding disorders;
(): deficient number of circulating platelets
() appear as a result of spontaneous, widespread hemorrhage
-Due to suppression or destruction of red bone marrow
Treatment: transfusion of concentrated platelets

Answer 6

Thrombocytopenia
Petechiae

Question 7

Bleeding disorders;
(): genetic disorder (mostly males)
several similar hereditary bleeding disorders
hemophilia A: most common due to factor 8 deficiency
hemophilia (): factor 9 deficiency
hemophilia C: factor 11 deficiency
Symptoms: prolonged bleeding
Treatment: injection of genetically engineered factors

Answer 7

hemophilia
B

Question 8

Disseminated intravasular coagulation:
-both widespread clotting and severe bleeding
-widespread bleeding occurs in () blood vessels, blocking flow
() bleeding follows because residual blood is unable to clot
-Can occur in septicemia, incompatible blood transfusions

Answer 8

intact
severe