Disorders of Growth and Cancer – Part 2 Flashcards
1
Q
What is neoplasia?
A
- A neoplasm is an abnormal proliferation, detrimental to the host, and persists after the stimulus which caused it has ceased
- Autonomous and means disproportionate to known stimuli and generally irreversible
- Resembles normal tissues
2
Q
- What is dysplasia?
A
- Increasingly abnormal morphology of epithelial cancer with molecular abnormalities in common with invasive cancer
3
Q
What are the usual characteristics of benign neoplasms?
A
- Grow slowly
- Well circumscribed
- Often have fibrous ‘capsule’
- Don’t invade but compress adjacent tissue
- Don’t spread
4
Q
What are the usual characteristics of malignant neoplasms?
A
- May grow rapidly
- Often poorly circumscribed
- Usually no ‘capsule’
- Often invade and damage adjacent tissues
- Often metastasize
5
Q
What is a sarcoma?
A
- Connective tissue malignancy
6
Q
What is a carcinoma?
A
- Epithelial malignancy
7
Q
What is a lymphoma?
A
- Lymphoid malignancy
8
Q
What is a melanoma?
A
- Melanocytic malignancy
9
Q
What is a leukaemia?
A
- Malignancy of blood cells
10
Q
What is an astrocytoma?
A
- Malignancy of astrocytes
11
Q
What is a leiomyoma/leiomyosarcoma?
A
- Muscle (benign/malignant)
12
Q
What is a fibroma/fibrosarcoma?
A
- Fibrous tissue (benign/malignant)
13
Q
What is an osteoma/osteosarcoma?
A
- Bone (benign/malignant)
14
Q
What is an angioma/angiosarcoma?
A
- Vessels (benign/malignant)
15
Q
What is a chondroma/chondrosarcoma?
A
- Cartilage (benign/malignant)
