Disorders of Appetite Flashcards
define polydipsia
excessive thirst or excess drinking
define adipsia
- inappropriate lack of thirst
- with consequent failure to drink in order to correct hyperosmolality
define anorexia
lack or loss of appetite for food
define obesity
abnormal or excessive fat accumulation that presents a risk to health
polydipsic and adipsic disorders can be divided into?
primary
secondary
is primary or secondary polydipsia more common?
secondary
what can cause secondary polydipsia?
Medical issues that disrupt any step in osmoregulation or alter ADH
where is ADH stored?
posterior pituitary
causes of secondary polydipsia - chronic medical conditions
Diabetes insipidus & mellitus Kidney failure Conn’s syndrome Addison's disease Sickle cell anaemia
causes of secondary polydipsia - medications
Diuretics
Laxatives (Both result in dehydration)
Antidepressants
causes of secondary polydipsia - dehydration
Acute illness Sweating Fevers Vomiting Diarrhoea Underhydration
treatment of diabetes insipidus
desmopressin
common symptoms of diabetes
always tired frequent urination sudden weight loss poor wound healing sexual problems always hungry blurry vision numb or tingling feet always thirsty vaginal infections
causes of primary polydipsia
mental illness: psychogenic polydipsia, schizophrenia, depression, anxiety, anorexia, drug use
brain injuries
organic brain damage
why is polydipsia a problem?
Kidney and bone damage Headache Nausea Cramps Slow reflexes Slurred speech Low energy Confusion Seizures
list types of adipsia
A - most common
B
C
D
outline adipsia
^osmolality of urine > stimulates secretion of ADH > water retention > sensation of thirst decreases
recall the model by which osmoreceptors shrink in response to more concentrated plasma
push-activation model
eating disorders include?
binge eating disorder anorexia nervosa bulimia nervosa pica rumination syndrome avoidant/restrictive food intake disorder
signs of anorexia
Low BMI, continuous weight loss, amenorrhea, halitosis, mood swings, dry hair, skin & hair thinning
mechanism of anorexia
serotonin
what is measured when screening for obesity?
height
weight
abdominal girth
main physiological actions of GLP1 and GLP2
Stimulate insulin release
Inhibit glucagon release
PYY is important for?
satiety
