Diseases of the Stomach and Vomiting Flashcards
What are 4 main differences between vomiting and regurgitation?
Regurgitation has no prodromal signs Regurgitation is passive Regurgitation is usually shortly after feeding Undigested food (often sausage shaped)
What are 3 things you should consider from the history of the vomiting patient?
Recent dietary changes?
On any medication?
Recent anesthesia?
What are 2 questions you might ask about the quality of the vomit?
Blood or “coffee grains”?
Is it undigested/partially digested food?
T/F: Vomiting is a relfex.
True
Where is the vomiting center?
In the medulla
What do you see in the prodromal phase?
Hypersalivation
What are 4 possible ddx for acute gastritis?
Bad/rich food
FB
Toxins
Drugs
What are 3 possible ddx for chronic gastritis?
IBD (Lymphoplasmacytic)
Helicobacter
Physaloptera
What is a possible ddx for gastric outflow problems?
Idiopathic hypomotility
What are 3 possible ddx for infiltrative gastric dz?
IMB
Neoplasia
Pythiosis
What are your first 4 steps in approaching a vomiting patient?
Systemic evaluation
Fecal
Imaging
Therapy
What are 4 possible therapies for a vomiting patient?
Deworm
Drugs
Bland diet
Fluids (if indicated)
What diagnostic approach would you take with acute vomiting and not ill?
Non-specific rx
What diagnostic approach would you take with acute vomiting and an ill patient?
Non-specific rx and workup
What diagnostic approach would you take with a chronic (over 7 days) vomiting patient.
Non-specific rx
Treatment trials and work up (need to figure out wtf is going on)
Biopsy
What 4 things would you do if you have hematemesis?
Determine origin (GI vs Resp.)
Evaluate coagulation
MDB
Imaging
What is “chronic” vomiting?
More than 7 days of vomiting
NOTE: Relatively common in dogs and cats
What will you likely need to do for a definitive dx in a chronic vomiting case?
Biopsy
What 3 things can help you exclude systemic dz in a vomiting case?
Hx
Exam
Routine labs
What 3 systemic dz might be excluded if an eosinophilia is detected?
Allergies
IBD
Verminosis
If you have a hypochloremia on your biochemestry, what systemic dz can you exclude?
Stricture
What is NOT appropriate to do with a chonic vomiting dog?
Withhold food
When is a diet trial not appropriate?
In systemically unwell patients
Cats with ______ tend to vomit and a large percentage respond to diet moditication.
IBD
With a vomiting patient, what 3 general symptomatic therapies would you use?
Anti-emetics
Antacids/Gastroprotectants
Pro-kinetics
When is the use of anti-emetics contraindicated?
If a FB is suspected
What are the 3 most common anti-emetics that you would use with a vomiting patient?
Maropitant (central and peripheral)
Metoclopramide (central in dogs)
Ondansetron (central in cats, peripheral in dogs)
What are the 3 most common anti-ulcer meds that you would use with a vomiting patient?
H2 receptor
Omeprazole
Sucralfate
What is important to remember about Cimetidine?
It may interfere with the metabolism of other drugs
What 2 things are important to remember about Ranitidine?
It has a pro-kinetic effect
IV use may cause hypotension
What 4 things does endoscopy allow us to examine?
Esophagus
Sphincter
Stomach
Proximal duodenum
NOTE: Never leave without a biopsy souvenir
After what other procedure should you perform endoscopy?
After US
What is the underlying cause of chronic gastritis?
Cause is rarely identified
How is chronic gastritis classified?
According to cellular infiltrate
What is the most common type of chronic gastritis?
Lymphoplasmacytic
What 2 things can you do to help manage lymphoplasmacytic chronic gastritis?
Diet modification
Immunosuppressant medication
What bacteria is often identified in chronic gastritis?
Helicobacter
NOTE: In humans, is associated with gastric neoplasia
What are 3 things you’ll see on biopsy to help diagnose Helicobacter?
Associated inflammation
Intracellular location
Epithelium changes
What is the test of choice for diagnosing Helicobacter?
Cytobrush via endoscope
What are 2 tests that you can do for Helicobacter other than the cytobrush?
Biopsy Urease test (CLOtest)
Why is it not just enough to see Helicobacter to diagnose?
Because it could be normal
Why is it not just enough to see Helicobacter to diagnose?
Because it could be normal
What is the most common gastric tumor?
Adenocarcinoma
What 3 dog breeds most commonly get adenocarcinoma?
Belgian sheperds
Collies
Staffies
What is the clinical sign of adenocarcinoma?
Hematemesis
How is adenocarcinoma diagnosed and confirmed?
Diagnosed :US
Confirmed: Biopsy
Why do adenocarcinomas often have such a poor prognosis?
Because they are highly infiltrative and complete excision is difficult
What is the most common type of GI neoplasia in cats?
GI lymphoma
What is the best way to diagnose a GI neoplasia?
Surgical biopsy
NOTE: Take multiple
What is a high grade lymphoma?
Rapidly dividing, lymphoblasts
What is a low grade lymphoma?
Slowly dividing, lymphocytes
Which grade lymphoma responds rapidly to chemo?
High grade because of rapidly dividing cells
What do you need to confirm the grade of lymphoma?
Biopsy
What is the outcome of chemo in a cat with high grade lymphoma?
50-70%, survival time of 6-10 months
What is the outcome of chemo in a dog with high grade lymphoma?
Not good
How do you treat a low grade lymphoma?
Low dose, long term chemo (prednisolone)
What is the outcome of cats treated for low grade lymphoma?
68% complete remission
Mean survival 23 months
What is delayed gastric outflow?
Food in stomach for >8hrs post-ingestion
What is a clinical sign of delayed gastric outflow?
Projectile vomiting
What are 3 causes of delayed gastric outflow?
Intramural dz
Extramural compression
FB
What is the most common cause of outflow obstruction?
Pyloric stenosis
What are the 2 types of pyloric stenosis?
Congenital pyloric stenosis
Adult antral pyloric hypertrophy
NOTE: Both are progressive
Who most often has congenital pyloric stenosis?
Boxers
Boston Terriers
What is involved in the congenital pylori stenosis?
Usually only muscle
Who commonly gets adult antral pyloric hypertrophy?
Small breed dogs
What is involved in adult antral pyloric hypertrophy?
Muscle and mucosa