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1PATHO > DISEASES OF THE IMMUNE SYSTEM > Flashcards

DISEASES OF THE IMMUNE SYSTEM Flashcards

1
Q

PROTECT THE BODY FROM ANY OFFENDING AGENT

A

IMMUNE SYSTEM

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2
Q

RXN AGAINST OWN OWN TISSUE AND CELLS

A

AUTOIMMUNITY

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3
Q

CAUSE IMMUNODEFECIENCY

A

HYPOFXN

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4
Q

CAUSE TUMORS

A

DYSFXN

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5
Q

MECHANICAL BARRIER IN SKIN

A

KERATIN

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6
Q

NEUTRALIZES THE PRSENCE OF PATHOGENS

A

DEFENSINS

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7
Q

TO ELIMINATE MICROBES IN GIT

A

CILIA

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8
Q

TO LUBRICATE TO DELIVER IN CILIA

A

GOBLET

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9
Q

SECRETE CYTOKINES TO DELIVER IN AREA OF INFECTION

A

NEUTROPHILS

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10
Q

MOST COMMON APC IN T LYMPHO
SECRETE CYTOKINES FOR ANTIVIRAL DEFENSE
PREVENT PROLIFERATION

A

DEDRITIC CELLS

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11
Q

TISSUE-RESIDENT LYMPHOCYTES
NO T CELL ANTIGEN RECEP
SOURCE OF INFLAMMATORY CYTOKINE DURING EARLY PHASE OF INFLAM

A

INNATE LYMPHOID CELLS

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12
Q

EARLY PROTECTION

RECOG N DESTROY SEVERELY STRESSED ABNORMAL CELLS

A

NATURAL KILLER CELLS

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13
Q

WITH GRANULES THAT R SCRETED TO ACTIVATE OTHER CELLS
PRODUCE MANY MEDIATORS OF INFLAM
EVEN ENDO AND EPI CELLS

A

MAST CELLS

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14
Q

ACTIVATION OF COMPLEMENT SYSTEM

A

PLASMA CELLS

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15
Q

RECOGNIZE SHARED COMPONENTS ESSENTIAL FOR INFECTIVITY

A

PATTERN RECOGNITION RECEPTORS

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16
Q

RECOGNIZE DAMAGED AND INJURED CELLS

A

DAMAGE RECOGNITION MOLECULAR PATTERNS

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17
Q

BEST DEFINED PRR
HOMOLOGOUS TO DROSOPHILA
PRESENT IN PM AND ENDO

A

TOLL-LIKE RECEPTORS

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18
Q

GENE DEVELPOMENT IN FLY

A

DROSOPHILA

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19
Q

STIMULATES SYNTHESIS N SECRETION OF CYTOKINES N EXPRESSION OF ADHESION MOLECULES

A

NF-kB

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20
Q

STIM PRODUCTION OF ANTIVIRAL CYTOKINES TYPE I

A

INTERFERON REGULATORY FACTORS

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21
Q

CYSTOLIC

RECOG NECROTIC CELL PRODUCTS, URIC ACID, ATP, ION DISTURBANCES

A

NOD-LIKE RECEP

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22
Q

SIGNAL VIA CYSTOLIC MULTIPROTEIN

ACTIVATE CASPASE-1 CLEAVES IL-1

A

INFLAMMASOME

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23
Q

MEDIATOR OF INFLAMM, RECRUIT LEUKO, FEVER

A

IL-1

24
Q

IN PM,

DETECT FUNGAL GLYCANS

A

C-TYPE LECTIN RECEPTORS

25
Q

RETINOIC ACID INDUCIBLE GENE RECEPTOR
CYTOSOL
IN NUCLEIC ACID PF VIRUSES (ANTIVIRAL)

A

RIG-LIKE RECEPTORS

26
Q

RIG ARE ACTIVATED BY

A

STING PATHWAY

27
Q

EXCESSIVE ACTIVATION LEAD TO SYSTEMIC INFLAMMATORY DSE

A

INTERFERONOPATHIES

28
Q

RECOGNIZE SHORT BACT PEPTIDES WITH FORMYL METHIONYL RECEP

A

G-PROTEIN COUPLED RECEP

29
Q

RECOG MICROBIAL SUGAR

A

MANNOSE RECEPTORS

30
Q

RECEPTOR FOR IGG GC

A

CD16

31
Q

WHEN LYMPHOCYTE REPEATEDLY DIVIDE

A

CLONAL POPU

32
Q

ENZYME FOR THE RECOMBINATION

A

RAG 1 N 2

33
Q

ADHESION MOLECULES THAT ATTACH TO T CELLS

A

INTEGRINS

34
Q

USE EPSTEIN BARR VIRUS

A

CD21

35
Q

PEPTIDE DISPLAY SYSTEM OF PROTEINS FOR RECOG OF T CELLS (ANTIGEN)

A

MHC

36
Q

MHC IN HUMANS

A

HUMAN LEUKOCYTE ANTIGENS

37
Q

FOR ALL NUCLEOTIDE CELLS AND PLATELETS
CDB
HLA,B,C
ALPHA1,2,3

A

MHC C1

38
Q

HLD
CD4
FOR EXTRACELLULAR MICROBES

A

MHC C2

39
Q

MESSENGER MOLECULES

A

CYTOKINES

40
Q

MOLECULARLY DEFINED CYTOKINES

MEDIATE COMMU BET LEUKOCYTES

A

INTELEUKINS

41
Q

T
NK
ANTIVIRAL
HLA2

A

TNF

42
Q

T CELL

IL2 PROD

A

IL1

43
Q 
MACROPHAGES
T 
NK
STIM T N B CELL, NK CELLS
ACT MONOCYTE
A

IL2

44
Q

B CELLS
MACRO
FIBRO
ANTIVIRAL

A

TYPE 2 INTER

45
Q

B CELLS

A

IL2

46
Q

T CELLS
HLA CLASS 2
CLASS SWITCHING

A

1L4

47
Q

END STAGE MATURE BCELLS

DEVP N ACT OF EOS

A

IL5

48
Q

ENHANCE IgE PROD

MUCUS SECRETION

A

IL13

49
Q

VASOACTIVE MOST IMP

A

HISTAMINE

50
Q

CAUSE TISSUE DAMAGE N GENERATE KININS

CHYMASE, TRYPTASE

A

ENZYME

51
Q

HEPARIN, PACK AND STORE AMINE

A

PROTEOGLYCAN

52
Q

VASOGENIC

SPASMOGENIC

A

LEUKOTRIENE C4 D4

53
Q

CHEMOTACTIC

A

LEUKOTRIENE B4

54
Q

BRONCHOSPASM

A

PROSTAGLANDIN D2

55
Q

PLATELET AGGREGATION

A

PAF

1PATHO (4 decks)

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