Diseases of the esophagus Flashcards

1
Q

Cause of achalasia

A

loss of ganglion cells in myenteric plexus

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2
Q

Usual age of presentation of achalasia

A

btw 25 and 50

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3
Q

Pathophysiology of achalasia

A

autoimmune process

latent herpes simplex 1 infection

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4
Q

Effect of long standing achalasia

A

sigmoid deformity of esophagus

Hypertrophy of LES

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5
Q

Symptoms of achalasia

A

Dysphagia

regurgitation

chest pain

weight loss

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6
Q

dysphagia in achalasia

A

Both solid and liquid food dysphagia

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7
Q

Complications of advanced achalasia

A

bronchitis

pneumonia

lung abscess

SCC of lower oesophagus

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8
Q

Symptom that is frequent early in course of achalasia

A

chest pain due to oesophageal spasm

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9
Q

Symptom relief following treatment of achalasia

A

Chest pain does not decrease much

Dysphagia or regurgitation is relieved

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10
Q

DD for achalasia

A

chagas

DES

pseudoachalasia

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11
Q

protozoa and vector of chagas disease

A

Trypanasoma cruzi

reduvid or kissing bug

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12
Q

Causes of pseudoachalasia

A

carcinoma of gastric fundus or lower esophagus

paraneoplastic syndrome

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13
Q

Presentation of pseudoachalasia

A

abrupt onset of symptoms(<1 year)

advanced age

weight loss

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14
Q

Workup for pseudoachalasia

A

OGD

CT

EUSG

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15
Q

role of endoscopy in achalasia

A

exclusion of pseudoachalasia

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16
Q

Diagnosis of achalasia cardia

A

barium swallow x ray

esophageal manometry

17
Q

Diagnostic criteria for achalasia in esophageal manometry

A

absent peristalsis

impaired LES relaxation

18
Q

Most sensitive diagnostic test for achalasia

A

esophageal manometry

19
Q

Subtypes of achalasia

A

classic achalasia

achalasia with compression

spastic achalasia

20
Q

Drug therapy in achalasia

A

Nitrates

CCB

Botulinium toxin

sildinafil

21
Q

Botulinium toxin injection in achalasia

A

Improves dysphagia in atleast 66% of patients for 6 months

22
Q

Only durable therapies for achalasia

A

Pneumatic dilatation

Heller myotomy

23
Q

In achalasia Rx,Balloon is dilated to ______ cm

A

3-4

24
Q

Major complication of balloon dilatation

A

perforation

25
Q

Most common surgical procedure for achalasia

A

Laparoscopic heller myotomy with partial fundoplication

26
Q

Rx of refractory achalasia

A

Esophageal resection with gastric pullup or transverse colon interposition

Gastrostomy feeding

27
Q
A