Diseases Flashcards
Cystic Fibrosis
When is it dx?
What causes?
Present from birth dx as a child
It is a recessive gene that must be given by both parents.
Cystic Fibrosis
What is the mechination?
What does it effect?
Chloride transport is blocked and produces thickened mucous
Effects lungs, liver, pancreas, salivary glands and testes
Cystic Fibrosis
So what? What is the big deal?
Most serious is airway obstruction due to thickened secretions.
Cystic Fibrosis
Diagnostic test - lab values
Chloride sweat: 5-35 mEq/L is normal a positive for cystic fibrosis is 60-200mEq/L (Pilocarpine is given to cause pt to sweat) done twice
Cystic Fibrosis:
Assessment findings- General
Severe GERD ABD distension Fatty Stools (Steatorrhea) Vitamin deficiencies (at risk for Osteoporosis) Small body build Liver cirrhosis Sterility
Cystic Fibrosis
Assessment - Lungs
Frequent respiratory infections Chest congestion Limited exercise tolerance Cough Sputum production Sinus infection Decreased pulmonary function Crackles Hemoptysis Dyspnea Acidosis
Cystic Fibrosis
Tx
Cure=none daily pulmonary interventions to loosen secretions Vitamin replacement Pancreatic replacement Draining positions Chest percussion Medications Heliox Antibiotics
Cystic Fibrosis
Exacerbation
Increased chest congestion Increased coughing ***Crackles*** Increased mucous 10% decrease in FEV1 Weight loss & fatigue Ventilatory muscle retraction
Cystic Fibrosis
Tx of exacerbation
Improve airway clearance- medications, precussion
Prevent infection- antibiotics(Burkholderia cepacia
Increase o2- supplement Heliox
Cystic Fibrosis
Pt. education
Avoid others bodily fluids
Avoid contact with others(shaking hands, kissing)
Wash hands often
Adhere to medication
Cystic Fibrosis
Surgical Tx
lung or pancreatic transplant
double lung transplant
Cystic Fibrosis
not a candidate for lung transplant
Hx of noncompliance Self harm behaviors 5 yr hx of cancer Irreversible damage to kidney, heart, liver Systemic infection >55y.o
Lung Transplant
intubated for <48hrss prevent infection monitor for bleeding, infection, rejection Anti-rejection meds for life Avoid corticosteroids for 10-14 days Prophylactic antibiotics
Head and Neck Cancer
etiology
Slow growing squamous cells
Curable early on
Risks: pollution smoking
Spread to lymph nodes, muscle, bone, lungs, liver
Effects breathing, eating, facial appearance, self image speech and communication
Head and Neck Cancer
locations
Mouth Throat Larynx Salivary Glands Thyroid Paranasal sinuses Lymph nodes in upper neck
Head and Neck Cancer
risks
Alcohol and Tobacco
Men
>60
North America
Head and Neck Cancer
warning signs
Pain Shortness of breath difficulty swallowing change in mouth oral lesion that wont heal numbness change of denture fit burning sensation with eating ear pain voice change persistent sore throat late stage= anorexia
Head and Neck Cancer
testing
Physical Lab tests- CBS, urinalysis, liver, kidney Panendoscopy X-rays, skull, neck, sinuses, chest CT scan MRI PET Biopsy
Head and Neck Cancer
Nursing priorities
Maintain patent airway
Decrease anxiety
Pt. will have body image disturbance
Head and Neck Cancer
Tx
Radiation(small cancer) S/E skin redness, edema, xerostomia, dehydration NOT done before surgery
Chemotherapy- used before and after surgery or radiation, decreases WBC, dehydration, hypotension
Surgery
Supraglottic method of swallowing
Pt. siting upright Clear throat take deep breath 1/2 teaspoon to 1 teaspoon of food per bite hold breath and bear down swallow twice breathe normally
Communication Post laryngectomy
Esophageal- burping
Mechanical-battery powered uses air
Tracheoesophageal- puncture b/w trachea and esophagus covering of stoma to create words
Lung Cancer
Etiology
Poor survival rate, high rate metastasis
Occurs as a result of inhaled substances Tobacco, smoke, dusts
Lung Cancer
Risk Factors
Cigarette smoke
Inhaled irritants
Air pollution
Tp53 gene
Lung Cancer
Bronchogenic Carcinomas
small cell: rapid growth spread easily secretes hormones non-small adenocarinoma squamous cell large cell
Lung Cancer
Assessment
Smoking hx Sputum Chronic cough hemoptysis wheezing shortnes of breath dull, aching chest pain pain! hoarseness dysphagia finger clubbing weight loss
Pulmonary Arterial Hypertension
pathophysiology
Cause unknown
occurs in the absence of other lung diseases
found most often in women between the ages of 20-40
PAH
assessment findings
Dyspnea
Fatigue
Chest Pain
Syncope
Cor Pulmonale
What is it?
Right sided heart failure
S&S dependent edema, engorged jugular veins, enlarged liver.
results in: Death or heart transplant
PAH
Diagnosis
Right side heart cath to measure pulmonary pressure normal pressure 8-25 mm Hg PAH >25mmHg Ventilation Perfusion scans Pulmonary Function Test reduced capacity CT
PAH
Tx
Drug therapy CA Channel blockers(procardia, cardizem, endothelin receptor antagonist[relax blood vessels–> hypotension], IV prostacyclins[ decrease pulmonary pressure, increase blood flow to lungs IV or SQ], Coumadin)
Digoxin and Diuretics can be used due to hypertrophy
With these drugs monitor Hypertension and Syncope(fainting)
Heart or lung transplant
INR theraputic 1.5-2.0
Use K with Lasix and Demadex
Flolon Therapy for PAH
IV or SQ
Continuous infusion, have back up batteries, go to ER immediately is interruption occurs
Use aseptic technique(central line)
CBC q 7days