Diseases Flashcards
Measles
Corzya at start Dry cough Red eyes Classic descending exanthema of measles Koplik spots in the mouth
Parkinsons quintet
2 or more signs = parkinsons
- Tremor at rest
- Rigidity
- Bradykinesia
- Postural instability
- Gait freezing
Cushings
Plethoric moon face + thin extremities + muscle weakness
Cushings investigations
2 of
Overnight 1mg Dexamethasone suppression test
Late night salivary cortisol (2x)
24hr urinary free cortisol (2x)
Primary hyperaldosteronism
Aka conns Htn Weakness from low k High na Cramps Pokyuria and polydipsia
Investigation for conns
Serum and urine aldosterone Plasma renin low Na high K low Alkalosis Imaging of adrenals - mri or ct
Addison’s disease
Fatigue + a/n/v + abdominal pain (+/- skin discoloration)
Weight loaa
Investigation for addisons
Elevated k Low na Short synacthen test is definitive Morning serum cortisol level Consider adrenal auto antibodies and ?calcification of adrenals
Phaeochromocytoma investigation
Series of 3x 24hr free catecholamines
Ct or mri abdomen
Vestibular neuritis
acute or subacute rotatory vertigo, nausea, NO hearing loss
if severe prednisone 1mg/kg up to 75mg PO mane for 5 days then taper over 15 days
Hypercalcemia
bones, moans, stones, abdominal groans
weakness + constipation + polyuria
hypocalcemia
cramps + confusion + tetany
Carcinoid symptoms & ix
facial flushing + diarrhea + valvular heart disease
serum chromograna A + urine 5HA, hepatic USS
Reactive arthritis
urethritis + conjuncitivits +/- iritis + arthritis
from Chalmydia, or enteric such as Salmonella
Lichen planus
4 Ps papule purple polygonal pruritic