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Microbiology 233 UW O > Disease of the skin > Flashcards

Disease of the skin Flashcards

1
Q

Epidermis is part of what layer of the skin?

A

Upper

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2
Q

How is the epidermis beneficial to the body?

A

provides tightly packed skin and is an effective barrier

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3
Q

The dermis is the ….

A

layer below epidermis

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4
Q

Conduits for the skin are?

A

hair follicles

sweat and oil glands

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5
Q

Perspirations involves what?

A

moisture

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6
Q

how can perspiration inhibit microbes?

A

salt
Lysozyme hydrolyze peptidoglycan
Defensins are antimicrobial peptides

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7
Q

Can some microbes survive in perspiration/ moisture rich climates?

A

Many microbes can because it provides a nutrient source

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8
Q

What microbe is not inhibited by salt?

A

Staphylococcus

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9
Q

Are lysozymes bacteriocidal?

A

Yes

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10
Q

What are great nutrient rich moist areas for microbes to get into?

A

armpits and between toes

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11
Q

The name of small peptides?

A

defensins

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12
Q

What are some body cavities that mucous membranes line?

A

mouth, eyes, and nose

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13
Q

Normal microflora of skin is a hospitable environment?

A

It is not a hospitable environment

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14
Q

Dipthroids are pleomorphic meaning what?

A

ability of microorganisms to alter their morphology, biological functions or reproductive modes

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15
Q

What microbes metabolize sebum?

A

Propionibacterium acnes

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16
Q

corynebacterium likes what environment?

A

salty and dry- skin

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17
Q

Normal microbiota of skin are?

A

Gram +
Staphylococci
micrococci and Diphtheroid

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18
Q

What are not normally found on plates?

A

Micro colonies

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19
Q

Where are Staphlococci and microcoocci and diphthroids found?

A

crevices and cracked skin

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20
Q

Staphlococci shape clumps like what food?

A

grapes

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21
Q

What is a gram + and coagulase negative?

A

Staphylococcus epidermidis

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22
Q

Is Staphylococcus epidermidis opportunistic?

A

Yes

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23
Q

What does coagulase do?

A

set enzyme reaction of fibrin clots

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24
Q

What do clots protect cell from?

A

phagocytes

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25
Q

What is Gram + cocci and coagulase postive?

A

S. aureus

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26
Q

20% permanent resident and 60% transient for nasal passage inhabitiant of S. aureus? T or F

A

True

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27
Q

Which microbe is MRSA resistant?

A

S. aureus

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28
Q

Leukocidins affect wbc and kill them. T or F

A

T

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29
Q 
S. aureus is
antibiotic resistant
leukocidin
exfoliative toxin
super antigen
T or F?
A

T

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30
Q

Exfoliative toxin do what?

A

cause skin sloughing, looks boiled(red) and tender

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31
Q

What a superantigen?

A

Hyperactive immune system that may lead to death

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32
Q

Process of Super antigen?

A

hyperactive immune system-leads to shock- death

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33
Q

T cell mediated and proteins are responsible for which microbe?

A

Staphylococoal aureus

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34
Q

Biofilms are composed of ?

A

proteins and polysaccharides

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35
Q

Biofilms are random?

A

Not random

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36
Q

Biofilms can be found on catheters. What do the bacteria in a biofilm do?

A

bacteria modifies the environment for the next bacteria

37
Q

….. provides protection of antibiotic resistant biofilms?

A

develope

38
Q

May appear as pimples. They are infections of the hair?

A

Folliculitis

39
Q

Sty is what?

A

folliculitis of an eyelash

40
Q

Boil is also known as and what is it?

A

AKA furuncle- pus surrounded by inflamed tissue

41
Q

Which foliculitis is more serious?

A

furuncle

42
Q

Inflammation of tissue under skin that occurs because of failure to wall off furuncle is called what?

A

Carbuncle

43
Q

What does autoinnoculation ?

A

you spread it

44
Q

Impetigo is not an autoinoculation nd what is it?

A

It is an autoinnoculation. It is crusting (nonbullous) sores caused by scratching

45
Q

What is nonbullous impetego?

A

large patches

46
Q

Scalded skin syndrome is caused by

A

exfoliation protein and bullous impetego

47
Q

Impetego of the newborn is called

A

pemhigus neonatorum

48
Q

Staphylocococal skin infections can cause

a toxic …….. ………..

A

shock syndrome

49
Q

Toxic shock syndrome symptoms?

A

vomit, fever, sunburn reaction- progress to shock-organ failure

50
Q

Streptococcus pyogenes is a recognized subgroups by?

A

lancefield

51
Q

Group A beta-hemolytic streptococci is partial or total?

A

total

52
Q

Group …. is a serological type

A

A

53
Q

Erysipelas is a

A

streptococal skin infection

54
Q

Dermal infection
possible sepsis
starts with the face usually is which skin infection

A

Erysipelas

55
Q

Impetego is also caused by what bacteria?

A

streptococcal

56
Q

simple infection goes wrong quack and it is a flesh eating bacteria is called?

A

necrotizing fasciitis

57
Q

Invasive group A streptocococal infection are

A

Necrotizing fascitis

STSS- streptococcal toxic shock syndrome

58
Q

Necrotizing fasciitis involves non of the below?

Flesh eating bacteria
Certain M-protein type streptococci
Exotoxin A, superantigen

A

Involves all mentioned

59
Q

It is often associated with necrotizing fasciitis

A

Streptococcal toxic shock syndrome

60
Q

Exotoxin A is

A

super antigen- autoimmune like

61
Q

Streptococcal TSS is less common than Staphylococal TSS

A

True

62
Q

Which is more common in Bacteremia Staph or Strept?

A

Staph

63
Q

Pseudomonas aeruginosa is a

A

gram -

aeroibic rod

64
Q

produces blue-green pus

A

pyocyanin

65
Q

Pyocyanin metabolize variety of chemicals like, lots of antibiotic resistants and C= E source

A

disinfectants

66
Q

Pseudomonas aeruginosa makes exotoxin which do what?

A

release toxin

67
Q

Associated with pools, pool-type saunas and hot tubs?

A

Pseudomonas dermatitis

68
Q

Otitis externa refers to what?

A

swimmers ear

69
Q

indewlling medical devices common cause are

A

Pseudomonads

70
Q

bleach are effective on psuedomonads

T or F

A

T

71
Q

Pseudomonads like to target because they are opportunistic towards whom?

A

cystic fibrosis and burn victims

72
Q

Post burn infections make have

A

blue-green pus

73
Q

Sebum channels of hair follicles are blocked with shed skin cells are what type of acne?

A

Comedonal

74
Q

comedo acne are

A

whiteheads

75
Q

blackheads are

A

comedone form of acne

76
Q

Name the Inflamatory acnes

A

Propionibacterium acnes

77
Q

Propionibacterium acnes are

A

Gram +

anaerobic rod

78
Q

Propionibacterium acne metabolism release fatty acids and blank response follows?

A

inflammatory

79
Q

inflammatory response of fatty acids from propionibacterium acnes metabolism causes

A

pustules- low bumps and papules- raised red spots

80
Q 
isotretinoin- prevent sebum formation
Accutane= teratogenic
antibiotics- bactrim
visible blue light- kills P.
Benzoyl peroxide used to loosen clogged follicles 
treat what?
A

Acne

81
Q

Cysts deep in the skin filled with pus
Often leave permanent physical scarring
Sometimes leads to psychological scarring too
are what ?

A

Nodular cystic acne

82
Q

What is used to treat nodular cystic acne?

A

Accutane

83
Q

Red eyes are always conjunctivitis?

A

No, may be allerigies

84
Q

Conjunctivitis is also called are caused by

A

Haemophilus influenzae
Various microbes
Associated with unsanitary contact lenses

85
Q

Neisseria gonorrhoeae
Transmitted to a newborn’s eyes during passage through the birth canal.
Prevented by treatment of a newborn’s eyes with antibiotics
is what disease?

A

Neonatal gonorrheal opthalmia

86
Q

What is the bacteria disease of the eye called?

A

Chlamydia trachomatis

87
Q

Transmitted to a newborn’s eyes during passage through the birth canal
Spread through swimming pool water
Treated with tetracycline

A

Inclusion conjunctivitis

88
Q

Trachoma is the leading

A

cause of blindness worldwide

89
Q

Infection causes permanent scarring; scars abrade the cornea leading to blindness

A

Trachoma disease

Microbiology 233 UW O (3 decks)

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