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Microbiology 233 UW O > Disease of the skin > Flashcards

Disease of the skin Flashcards

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1
Q

Epidermis is part of what layer of the skin?

A

Upper

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2
Q

How is the epidermis beneficial to the body?

A

provides tightly packed skin and is an effective barrier

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3
Q

The dermis is the ….

A

layer below epidermis

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4
Q

Conduits for the skin are?

A

hair follicles

sweat and oil glands

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5
Q

Perspirations involves what?

A

moisture

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6
Q

how can perspiration inhibit microbes?

A

salt
Lysozyme hydrolyze peptidoglycan
Defensins are antimicrobial peptides

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7
Q

Can some microbes survive in perspiration/ moisture rich climates?

A

Many microbes can because it provides a nutrient source

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8
Q

What microbe is not inhibited by salt?

A

Staphylococcus

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9
Q

Are lysozymes bacteriocidal?

A

Yes

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10
Q

What are great nutrient rich moist areas for microbes to get into?

A

armpits and between toes

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11
Q

The name of small peptides?

A

defensins

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12
Q

What are some body cavities that mucous membranes line?

A

mouth, eyes, and nose

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13
Q

Normal microflora of skin is a hospitable environment?

A

It is not a hospitable environment

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14
Q

Dipthroids are pleomorphic meaning what?

A

ability of microorganisms to alter their morphology, biological functions or reproductive modes

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15
Q

What microbes metabolize sebum?

A

Propionibacterium acnes

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16
Q

corynebacterium likes what environment?

A

salty and dry- skin

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17
Q

Normal microbiota of skin are?

A

Gram +
Staphylococci
micrococci and Diphtheroid

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18
Q

What are not normally found on plates?

A

Micro colonies

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19
Q

Where are Staphlococci and microcoocci and diphthroids found?

A

crevices and cracked skin

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20
Q

Staphlococci shape clumps like what food?

A

grapes

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21
Q

What is a gram + and coagulase negative?

A

Staphylococcus epidermidis

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22
Q

Is Staphylococcus epidermidis opportunistic?

A

Yes

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23
Q

What does coagulase do?

A

set enzyme reaction of fibrin clots

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24
Q

What do clots protect cell from?

A

phagocytes

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25
What is Gram + cocci and coagulase postive?
S. aureus
26
20% permanent resident and 60% transient for nasal passage inhabitiant of S. aureus? T or F
True
27
Which microbe is MRSA resistant?
S. aureus
28
Leukocidins affect wbc and kill them. T or F
T
29
``` S. aureus is antibiotic resistant leukocidin exfoliative toxin super antigen T or F? ```
T
30
Exfoliative toxin do what?
cause skin sloughing, looks boiled(red) and tender
31
What a superantigen?
Hyperactive immune system that may lead to death
32
Process of Super antigen?
hyperactive immune system-leads to shock- death
33
T cell mediated and proteins are responsible for which microbe?
Staphylococoal aureus
34
Biofilms are composed of ?
proteins and polysaccharides
35
Biofilms are random?
Not random
36
Biofilms can be found on catheters. What do the bacteria in a biofilm do?
bacteria modifies the environment for the next bacteria
37
..... provides protection of antibiotic resistant biofilms?
develope
38
May appear as pimples. They are infections of the hair?
Folliculitis
39
Sty is what?
folliculitis of an eyelash
40
Boil is also known as and what is it?
AKA furuncle- pus surrounded by inflamed tissue
41
Which foliculitis is more serious?
furuncle
42
Inflammation of tissue under skin that occurs because of failure to wall off furuncle is called what?
Carbuncle
43
What does autoinnoculation ?
you spread it
44
Impetigo is not an autoinoculation nd what is it?
It is an autoinnoculation. It is crusting (nonbullous) sores caused by scratching
45
What is nonbullous impetego?
large patches
46
Scalded skin syndrome is caused by
exfoliation protein and bullous impetego
47
Impetego of the newborn is called
pemhigus neonatorum
48
Staphylocococal skin infections can cause | a toxic ........ ...........
shock syndrome
49
Toxic shock syndrome symptoms?
vomit, fever, sunburn reaction- progress to shock-organ failure
50
Streptococcus pyogenes is a recognized subgroups by?
lancefield
51
Group A beta-hemolytic streptococci is partial or total?
total
52
Group .... is a serological type
A
53
Erysipelas is a
streptococal skin infection
54
Dermal infection possible sepsis starts with the face usually is which skin infection
Erysipelas
55
Impetego is also caused by what bacteria?
streptococcal
56
simple infection goes wrong quack and it is a flesh eating bacteria is called?
necrotizing fasciitis
57
Invasive group A streptocococal infection are
Necrotizing fascitis | STSS- streptococcal toxic shock syndrome
58
Necrotizing fasciitis involves non of the below? Flesh eating bacteria Certain M-protein type streptococci Exotoxin A, superantigen
Involves all mentioned
59
It is often associated with necrotizing fasciitis
Streptococcal toxic shock syndrome
60
Exotoxin A is
super antigen- autoimmune like
61
Streptococcal TSS is less common than Staphylococal TSS
True
62
Which is more common in Bacteremia Staph or Strept?
Staph
63
Pseudomonas aeruginosa is a
gram - | aeroibic rod
64
produces blue-green pus
pyocyanin
65
Pyocyanin metabolize variety of chemicals like, lots of antibiotic resistants and C= E source
disinfectants
66
Pseudomonas aeruginosa makes exotoxin which do what?
release toxin
67
Associated with pools, pool-type saunas and hot tubs?
Pseudomonas dermatitis
68
Otitis externa refers to what?
swimmers ear
69
indewlling medical devices common cause are
Pseudomonads
70
bleach are effective on psuedomonads | T or F
T
71
Pseudomonads like to target because they are opportunistic towards whom?
cystic fibrosis and burn victims
72
Post burn infections make have
blue-green pus
73
Sebum channels of hair follicles are blocked with shed skin cells are what type of acne?
Comedonal
74
comedo acne are
whiteheads
75
blackheads are
comedone form of acne
76
Name the Inflamatory acnes
Propionibacterium acnes
77
Propionibacterium acnes are
Gram + | anaerobic rod
78
Propionibacterium acne metabolism release fatty acids and blank response follows?
inflammatory
79
inflammatory response of fatty acids from propionibacterium acnes metabolism causes
pustules- low bumps and papules- raised red spots
80
``` isotretinoin- prevent sebum formation Accutane= teratogenic antibiotics- bactrim visible blue light- kills P. Benzoyl peroxide used to loosen clogged follicles treat what? ```
Acne
81
Cysts deep in the skin filled with pus Often leave permanent physical scarring Sometimes leads to psychological scarring too are what ?
Nodular cystic acne
82
What is used to treat nodular cystic acne?
Accutane
83
Red eyes are always conjunctivitis?
No, may be allerigies
84
Conjunctivitis is also called are caused by
Haemophilus influenzae Various microbes Associated with unsanitary contact lenses
85
Neisseria gonorrhoeae Transmitted to a newborn's eyes during passage through the birth canal. Prevented by treatment of a newborn's eyes with antibiotics is what disease?
Neonatal gonorrheal opthalmia
86
What is the bacteria disease of the eye called?
Chlamydia trachomatis
87
Transmitted to a newborn's eyes during passage through the birth canal Spread through swimming pool water Treated with tetracycline
Inclusion conjunctivitis
88
Trachoma is the leading
cause of blindness worldwide
89
Infection causes permanent scarring; scars abrade the cornea leading to blindness
Trachoma disease

Microbiology 233 UW O (3 decks)

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