Ch 25 Microbial diseases of the digestive system Flashcards

1
Q
Millions of bacteria per ml of saliva
700 species in mouth
Large numbers in large intestine
100 billion bacteria per gram of feces
Defenses
Stomach acid
Small intestine: Paneth cells
phagocytes
Defensins
lysozyme
A

normal microflora

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2
Q

Diseases of Lower Digestive System

A
Infection: Growth of a pathogen
Incubation is from 12 hours to 2 weeks
Fever
Intoxication: Ingestion of toxin
Symptoms appear 1 to 48 hours after ingestion
Gastroenteritis: Diarrhea, dysentery
Treatment: Oral rehydration therapy
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3
Q

Caused by Salmonella typhi
Bacteria spread throughout body in phagocytes
1–3% of recovered patients become chronic carriers

A

Typhoid Fever

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4
Q

Vibrio cholerae serotypes, O:1, O:139, that produce cholera toxin
Toxin causes host cells to secrete Cl–, HCO–, and water

Usually from contaminated crustaceans or mollusks
V. parahaemolyticus
V. vulnificus

A

Cholera

Noncholera vibrios

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5
Q

Escherichia coli Gastroenteritis

A

Pathogenic E. coli
Attach to intestinal cells with fimbriae
Produce toxins
May aggregate

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