Direct Renin Inhibitor Flashcards
What is the primary action of Direct Renin Inhibitors?
They inhibit the activity of renin, leading to decreased production of angiotensin I and II.
Which generic name is commonly associated with the Direct Renin Inhibitor class?
Aliskiren.
True or False: Direct Renin Inhibitors are primarily used to treat hypertension.
True.
What class of drugs do Direct Renin Inhibitors belong to?
Antihypertensive drugs.
Fill in the blank: The mechanism of action of Direct Renin Inhibitors involves the inhibition of _____ production.
angiotensin.
What is a common adverse effect of Direct Renin Inhibitors?
Diarrhea.
Multiple choice: Which of the following is NOT an adverse effect of Direct Renin Inhibitors? A) Hyperkalemia B) Cough C) Rash
B) Cough.
What should be monitored when a patient is taking a Direct Renin Inhibitor?
Blood pressure and potassium levels.
True or False: Direct Renin Inhibitors can be used in combination with ACE inhibitors.
False.
What is the recommended nursing intervention when administering Direct Renin Inhibitors?
Educate the patient about potential side effects.
Fill in the blank: Direct Renin Inhibitors may cause _____ in patients with renal impairment.
acute kidney injury.
What is a serious adverse effect that requires immediate medical attention when using Direct Renin Inhibitors?
Angioedema.
Multiple choice: Which population should avoid Direct Renin Inhibitors? A) Pregnant women B) Elderly C) Diabetic patients
A) Pregnant women.
True or False: Direct Renin Inhibitors have a fast onset of action.
True.
What is the typical dosing frequency for Aliskiren?
Once daily.
Fill in the blank: Direct Renin Inhibitors should not be taken with _____ as it may decrease absorption.
high-fat meals.
What is the main benefit of using Direct Renin Inhibitors over other antihypertensive classes?
They provide a direct blockage of the renin-angiotensin system.
Multiple choice: Which of the following is a contraindication for Direct Renin Inhibitors? A) Allergy to Aliskiren B) History of heart failure C) Stage 2 hypertension
A) Allergy to Aliskiren.
True or False: Direct Renin Inhibitors can cause hypotension.
True.
What should patients be advised to report while on Direct Renin Inhibitors?
Signs of allergic reactions or swelling.
Fill in the blank: Direct Renin Inhibitors are often used as part of a _____ regimen for hypertension.
multidrug.
What is the primary reason for caution in patients with renal artery stenosis taking Direct Renin Inhibitors?
Risk of worsening renal function.
What is the effect of Direct Renin Inhibitors on the renin-angiotensin-aldosterone system?
They lower the levels of angiotensin II and aldosterone.
True or False: Direct Renin Inhibitors can be used safely in patients with a history of angioedema.
False.
What is the ideal patient education regarding the timing of taking Direct Renin Inhibitors?
Take at the same time each day for consistency.
