Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

2021 Pharm 2 > digoxin > Flashcards

digoxin Flashcards

1
Q

use

A
  • second-line Tx for
    • HF
    • dysrhythmias (a-fib and flutter)
    • paroxysmal SVT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

inotropy

A

force of muscle contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

+ inotropic effect

A
  • ↑ force of myocardial contraction
  • improves SV
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

chronotropy

A

affecting a time or rate, as in HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

– chronotropic effect

A
  • ↓ HR
  • slows rates of
    • SA node depolarization
    • impulses through heart’s conduction system
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the overall effect of dig?

A

gives ventricles more time to fill → ↑ SV and CO

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

dig complications

A
  • dysrhythmias
  • cardiotoxicity
  • toxicity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

dig-induced cardiotoxicity →

A

bradycardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

conditions that ↑ risk of digoxin-induced dysrhythmias

A
  • hypokalemia
  • ↑ serum digoxin
  • heart dz
  • older age
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

first sign of dig toxicity

A

GI effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

S/Sx of dig toxicity

A
  • GI effects
    • anorexia
    • N&V
    • abd pain
  • CNS effects
    • fatigue
    • weakness
    • vision changes
      • diplopia
      • blurred vision
      • yellow-gree or white halos
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

GI effects of dig toxicity

A
  • anorexia
  • N&V
  • abd pain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

CNS effects of dig toxicity

A
  • fatigue
  • weakness
  • vision changes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

vision changes r/t dig toxicity

A
  • diplopia
  • blurred vision
  • yellow-green or white halos
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

baseline/periodic labs for dig therapy

A
  • dig level (0.5–2.0 ng/mL)
  • serum K+ (3.5–5.0 mEq/L)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

therapeutic dig level

A

0.5–2.0 ng/mL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

K+ serum level reference range

A

3.5–5.0 mEq/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What do you check before administering dig?

A

HR and rhythm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What HRs warrant holding/notifying provider before giving dig?

A
  • adult: < 60
  • child: < 70
  • infant: < 90
20
Q

Dig dosage is based on what two factors?

A
  • serum level
  • pt response
21
Q

When should dig be administered?

A

at the same time daily

22
Q

What two drugs may be prescribed along with dig?

A
  • K+ supplement
  • diuretic
23
Q

IV dig admin

A
  • infuse over at least 5 min
  • monitor for dysrhythmias
24
Q

What information should you gather before contacting the provider about dig administration?

25
evaluation for dig therapy
* control of HF * absence of dysrhythmias
26
missed dose
**do not double** next dose
27
toxicity Sx for pt to report
* fatigue * weakness * vision changes * **GI effects**
28
diet changes for dig therapy
* high-K+ foods * green leafy veggies * bananas * potatoes
29
hypokalemia Sx for pt to report
* N&V * general weakness
30
pt ed: taking dig
* monitor pulse before taking * hold med report changes to provider * irregular rate with early or extra beats * \< 60 bpm or \> 100 bpm * take at same time daily
31
What should pts avoid while taking dig?
* OTC meds * prevent AE and interactions * talk to provider before taking
32
contraindications
* disturbances in ventricular rhythm * v-fib * ventricular tachycardia * 2nd- and 3rd-degree heart block
33
precautions
* hypokalemia * partial AV block * advanced HF * renal insufficiency
34
thiazide or loop diuretics + dig =
* hypokalemia (monitor levels) * ↑ risk of dysrhythmias
35
ACE inhibitors or ARBs + dig =
* ↑ risk of hyperkalemia → ↓ effects of digoxin * use cautiously with K+ or K+-sparing diuretics * monitor K+
36
sympathomimetics + dig =
* complement inotropic action, ↑ rate and force of heart muscle contraction * may be beneficial, but also may ↑ risk of dysrhythmias * monitor ECG * pt ed: report palpitations
37
quinidine + dig =
* ↑ risk of dig toxicity * avoid concurrent use
38
verapamil + dig =
* ↑ plasma levels of dig * ↓ dig dose * usually avoided because verapamil (cardiosuppressive) can counteract dig
39
antacids + dig =
* ↓ dig absorption and effect * talk to provider before taking
40
What drugs should be stopped if dig toxicity occurs?
* dig * K+-wasting meds
41
What drugs can treat dysrhythmias in dig toxicity?
* lidocaine * phenytoin
42
Treat bradycardia r/t dig toxicity with \_\_\_\_\_\_.
atropine
43
interventions for excessive dig overdose
* to bind in GI tract * activated charcoal * cholestyramine * ​​to bind in blood * **Digibind**
44
class
* cardiac glycoside * antiarrhythmic * inotropic
45
trade name
Lanoxin
46
dig effects
* ↓ electrical conduction through AV node * ↑ myocardial contraction * ↑ SV * ↑ CO

2021 Pharm 2 (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions