digoxin Flashcards

1
Q

use

A
  • second-line Tx for
    • HF
    • dysrhythmias (a-fib and flutter)
    • paroxysmal SVT
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2
Q

inotropy

A

force of muscle contraction

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3
Q

+ inotropic effect

A
  • ↑ force of myocardial contraction
  • improves SV
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4
Q

chronotropy

A

affecting a time or rate, as in HR

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5
Q

– chronotropic effect

A
  • ↓ HR
  • slows rates of
    • SA node depolarization
    • impulses through heart’s conduction system
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6
Q

What is the overall effect of dig?

A

gives ventricles more time to fill → ↑ SV and CO

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7
Q

dig complications

A
  • dysrhythmias
  • cardiotoxicity
  • toxicity
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8
Q

dig-induced cardiotoxicity →

A

bradycardia

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9
Q

conditions that ↑ risk of digoxin-induced dysrhythmias

A
  • hypokalemia
  • ↑ serum digoxin
  • heart dz
  • older age
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10
Q

first sign of dig toxicity

A

GI effects

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11
Q

S/Sx of dig toxicity

A
  • GI effects
    • anorexia
    • N&V
    • abd pain
  • CNS effects
    • fatigue
    • weakness
    • vision changes
      • diplopia
      • blurred vision
      • yellow-gree or white halos
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12
Q

GI effects of dig toxicity

A
  • anorexia
  • N&V
  • abd pain
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13
Q

CNS effects of dig toxicity

A
  • fatigue
  • weakness
  • vision changes
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14
Q

vision changes r/t dig toxicity

A
  • diplopia
  • blurred vision
  • yellow-green or white halos
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15
Q

baseline/periodic labs for dig therapy

A
  • dig level (0.5–2.0 ng/mL)
  • serum K+ (3.5–5.0 mEq/L)
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16
Q

therapeutic dig level

A

0.5–2.0 ng/mL

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17
Q

K+ serum level reference range

A

3.5–5.0 mEq/L

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18
Q

What do you check before administering dig?

A

HR and rhythm

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19
Q

What HRs warrant holding/notifying provider before giving dig?

A
  • adult: < 60
  • child: < 70
  • infant: < 90
20
Q

Dig dosage is based on what two factors?

A
  • serum level
  • pt response
21
Q

When should dig be administered?

A

at the same time daily

22
Q

What two drugs may be prescribed along with dig?

A
  • K+ supplement
  • diuretic
23
Q

IV dig admin

A
  • infuse over at least 5 min
  • monitor for dysrhythmias
24
Q

What information should you gather before contacting the provider about dig administration?

A

VS

25
Q

evaluation for dig therapy

A
  • control of HF
  • absence of dysrhythmias
26
Q

missed dose

A

do not double next dose

27
Q

toxicity Sx for pt to report

A
  • fatigue
  • weakness
  • vision changes
  • GI effects
28
Q

diet changes for dig therapy

A
  • high-K+ foods
    • green leafy veggies
    • bananas
    • potatoes
29
Q

hypokalemia Sx for pt to report

A
  • N&V
  • general weakness
30
Q

pt ed: taking dig

A
  • monitor pulse before taking
    • hold med report changes to provider
    • irregular rate with early or extra beats
    • < 60 bpm or > 100 bpm
  • take at same time daily
31
Q

What should pts avoid while taking dig?

A
  • OTC meds
    • prevent AE and interactions
    • talk to provider before taking
32
Q

contraindications

A
  • disturbances in ventricular rhythm
    • v-fib
    • ventricular tachycardia
    • 2nd- and 3rd-degree heart block
33
Q

precautions

A
  • hypokalemia
  • partial AV block
  • advanced HF
  • renal insufficiency
34
Q

thiazide or loop diuretics + dig =

A
  • hypokalemia (monitor levels)
  • ↑ risk of dysrhythmias
35
Q

ACE inhibitors or ARBs + dig =

A
  • ↑ risk of hyperkalemia → ↓ effects of digoxin
    • use cautiously with K+ or K+-sparing diuretics
    • monitor K+
36
Q

sympathomimetics + dig =

A
  • complement inotropic action, ↑ rate and force of heart muscle contraction
  • may be beneficial, but also may ↑ risk of dysrhythmias
  • monitor ECG
  • pt ed: report palpitations
37
Q

quinidine + dig =

A
  • ↑ risk of dig toxicity
  • avoid concurrent use
38
Q

verapamil + dig =

A
  • ↑ plasma levels of dig
  • ↓ dig dose
  • usually avoided because verapamil (cardiosuppressive) can counteract dig
39
Q

antacids + dig =

A
  • ↓ dig absorption and effect
  • talk to provider before taking
40
Q

What drugs should be stopped if dig toxicity occurs?

A
  • dig
  • K+-wasting meds
41
Q

What drugs can treat dysrhythmias in dig toxicity?

A
  • lidocaine
  • phenytoin
42
Q

Treat bradycardia r/t dig toxicity with ______.

A

atropine

43
Q

interventions for excessive dig overdose

A
  • to bind in GI tract
    • activated charcoal
    • cholestyramine
  • ​​to bind in blood
    • Digibind
44
Q

class

A
  • cardiac glycoside
  • antiarrhythmic
  • inotropic
45
Q

trade name

A

Lanoxin

46
Q

dig effects

A
  • ↓ electrical conduction through AV node
  • ↑ myocardial contraction
  • ↑ SV
  • ↑ CO