Digestive System Flashcards
Intracellular digestion
As part of metabolism, involves the oxidation of glucose and fatty acids for energy
Alimentary canal
Runs from the mouth to the anus and is sectioned off by sphincters, or circular smooth muscles around the canal that can contract to allow compartmentalization of function
Mechanical digestion
The physical breakdown of large food particles into smaller food particles, but does not involve breaking chemical bonds
Chemical digestion
The enzymatic cleavage of chemical bonds, such as the peptide bonds of proteins or the glycosidic bonds of starches
Absorption
Involves the transport of products of digestion from the digestive tract into the circulatory system for distribution to the body’s tissues and cells.
Pathway of food in the digestive tract
Oral cavity/mouth –> pharynx –> esophagus –> stomach –> small intestine –> large intestine –> rectum
Enteric nervous system
A collection of one hundred million neurons that govern the function of the gastrointestinal system –> trigger peristalsis
Mastication
Chewing: helps to increase surface area-to-volume ratio of food, creates more surface area for enzymatic digestion as it passes through the gut tube
Salivary amylase
Capable of hydrolyzing starch into smaller sugars (maltose and dextrins)
Lipase
Catalyzes the hydrolysis of lipids
Pharynx
Cavity that leads from the mouth and posterior nasal cavity to the esophagus
3 parts of the pharynx
Nasopharynx (behind the nasal cavity), the oropharynx (at the back of the mouth), and the laryngopharynx (above the vocal cords)
Epiglottis
A cartilaginous structure that folds down to cover the laryngeal inlet –> prevents food from entering the larynx
Esophagus
Muscular tube that connects the pharynx to the stomach
Muscular composition of esophagus
Top third of the esophagus is composed of skeletal muscle, bottom third is composed of smooth muscle, and middle third is a mix of both
Emesis
vomiting
Upper esophageal sphincter
Where swallowing is inititaed; in the orpharynx
Lower esophageal sphincter (cardiac sphincter)
Relaxes and opens to allow the passage of food
What are the 3 main energy sources for the body
Carbohydrates, fats, and proteins
Stomach
Highly muscular organ with a capacity of approximately 2 liters. In humans, the stomach is located in the upper left quadrant of the abdominal cavity, underneath the diaphragm.
The 4 main anatomical divisions of the stomach
The fundus and body, which contain mostly gastric glands,
antrum and pylorus, which contain mostly pyloric glands.
Lesser curvature
The internal curvature of the stomach
Greater curvature
External curvature of the stomach
Rugae
Lining of the stomach is thrown into folds
Gastric glands
Respond to signals from the vagus nerve of the parasympathetic nervous system, which is activated by the brain in response to the sight, taste, and smell of food.
What are the 3 different cell types in gastric glands
Mucous cells, chief cells, and parietal cells
Mucous cells
Produce the bicarbonate-rich mucus that protects the muscular wall from the harshly acidic (pH = 2) and proteolytic environment of the stomach
Gastric juice
A combination of secretions from the other 2 cell types in the gastric glands: chief cells and parietal cells
Chief cells
Secretes pepsinogen: the inactive, zymogen form of pepsin, a proteolytic enzyme.
Parietal cells
Secrete hydrogen ions in the stomach as hydrochloric acid, which cleave pepsinogen to pepsin. Also secretes intrinsic factor.
Pepsin
Digests proteins by cleaving peptide bonds near aromatic amino acids, resulting in short peptide fragments