Digestive System Flashcards
How does ingested food move through the digestive tract?
- Swallowing, which consists of three phases:
- the voluntary buccal phase and the involuntary pharyngeal and esophageal phases.
- Peristalsis: involuntary radial contraction and relaxation of the muscular externa of the digestive tract.
- Segmentation of small intestine and haustral contractions in large intestines: non-adjacent portions of the intestines involuntarily contract and relax to move the chyme.
What are the four types of cells in the gastric glands of the stomach gastric glands of the stomach mucosa?
- Endocrine cells (G cells) release hormones such as gastrin into the blood
- Parietal cells secrete intrinsic factor (required for the absorption of vitamin B12 in the small intestine), and hydrochloride acid (HCI), which lowers the pH of gastric juice.
- Chief cells secrete pepsinogen and gastric lipase.
- Mucous cells secrete bicarbonate- containing mucus to protect the stomach from the acidity and digestive enzymes.
How does ingested food move through the digestive tract?
Swallowing, which consists of three phases: The voluntary buccal phase and the involuntary pharyngeal and esophageal phase
Peristalsis: involuntary radial contraction and relaxation of the muscularis externa of the digestive tract.
Segmentation of small intestines and haustal contractions in large intestines: non-adjacent portions of the intestines involuntary contract and relax to move the chyme.
What are the four types of cells in the gastric glands of the stomach mucosa?
Endocrine cells (G cells) release hormones such as gastrin into the blood.
Parietal cells secrete intrinsic factor (required for the absorption of vitamin B12 in the small intestines), and hydrochloric acid (HCI), which lowers the pH of gastric juice.
Chief cells secrete pepsinogen and gastric lipase.
Mucous cells secrete bicarbonate-containing mucus to protect the stomach from the acidity and digestive enzymes.
What are the four main regions of stomach?
Cardiac region: area where food is emptied into the stomach
Fundus: most superior region of the stomach
Body: the largest, most central region, curves toward the right to form a āJā shape, with a lesser curvature and a greater curvature
Pylorus: funnel-shaped region below the body. The pyloric sphincter is the valve that regulates the release of small amounts of chyme into the small intestine.
How does muscle contraction occur?
When an action potential (electrical signal) reaches a muscle fiber, calcium ions are released. According to the sliding filament model of muscle contraction, these calcium ions bind to the myosin and actin, which assists in the binding of the myosin heads of the thick filaments to the actin molecules of the thin filaments. ATP released from glucose provides the energy necessary for the contraction.
What is bile and what is its function?
Bile is a yellow-green solution of bile salts, pigments (mainly bilirubin from the breakdown of hemoglobin), cholesterol, and electrolytes. Only the bile salts play a role in digestion, and they do so mechanically (not enzymatically) by emulsifying fats into smaller globules called micelles that can be acted on by lipases in the small intestine. Bile enhances the absorption of the fat soluble vitamins. Liver cells synthesize bile salts from cholesterol.
What are the primary roles of the liver?
Production of bile, metabolic functions like blood sugar regulation, and detoxification.
What are the three primary layers skin is composed of, respectively, from superficial to deep?
Epidermis: consists entirely of epithelial cells, does not contain any blood vessels. Most epidermal cells are keratinized.
Dermis: consists mostly of connective tissue, contains blood vessels, sensor receptors, hair follicles, sebaceous glands, and sweat glands. The dermis also contains elastin and collagen fibers.
Hypodermis: subcutaneous layer consists of fat and connective tissue, which binds the skin to the underlying muscles, and helps insulate.
What are the functions of the pancreas?
As an endocrine gland, it releases insulin, glucagon, and somatostatin into the blood. As an exocrine gland, acinar cells of the pancreas release enzyme-rich solution that raises the pH. Pancreatic amylase digests starch, and pancreatic lipase digests fats proteases are released in their inactive form, but are activated in the small intestine. Nucleases digest nucleic acids.
Where does most chemical digestion take place?
The small intestine
Brush border enzymes of the microvilli (as well as pancreatic enzymes) break down carbohydrates, fats, proteins, and nucleic acids into smaller components which are then absorbed
What are the three regions of the small intestine?
Duodenum: shortest and widest; receives chyme from the stomach and neutralizing digestive juices from the pancreas. Most of the chemical digestion of food occurs here; only really absorbs iron.
Jejunum: main site of absorption; dense microvilli
Ileum: longest, narrowest; absorbs vitamin B12, bile salts, and any nutrients that were not absorbed by the jejunum
What are the primary functions of the large intestine?
The absorption of vitamin K, biotin, sodium ions, chloride ions, and water
By the time chyme reaches the large intestine, most of the water (approximately 80%) has already been absorbed by the small intestine. As the chyme is pushed through the colon 90% of the remaining liquid is absorbed, leaving a mass of indigestible food, water, and bacteria.
What are the primary regions and structures of the large intestine?
The large intestine begins at the ileocecal valve, which leads to a pouch called the cecum, which receives chyme from the small intestine. It is also the site of a blind-ended tube called the appendix. The middle portion is the colon, further subdivided into the ascending colon, transverse colon, descending colon, and sigmoid colon (becomes the rectum, which opens to the anus).
Mastication
voluntary act of chewing
Peristalsis
moves food from the pharynx to the esophagus to the stomach where an extra muscle layer helps to churn and mix the food.
Segmentation
occurs in the intestines in addition to peristalsis. Non-adjacent portions of the digestive tract contract and relax to move the chyme, partly digested food, back and forth.
The three pairs of major salivary glands:
the parotid, submandibular, and sublingual glands.
_____ begins the chemical breakdown of polysaccharides into simpler sugars, and ____ begins the breakdown of fats.
- Salivary amylase
- lingual lipase