DIGESTIVE SYSTEM Flashcards
Consists of a long muscular tube beginning
from the lips to the anus
Alimentary tract
– Salivary glands
– Liver
– Biliary tract
– Pancreas
Accessory organs
4 Layers
Mucosa
Submucosa
Tunica muscularis
Serosa
Lining epithelium
Mucosa
highly vascular loose CT;
contains fibroblasts, reticular and elastic
fibers, macrophages, aggregates of lymphoid
tissue
Lamina propria
thin layer of smooth
muscle which separates mucosa from
submucosa
Muscularis mucosa
Layer of dense CT containing many
blood vessels and a plexus of
sympathetic nerves called Meissner’s
plexus which controls the intrinsic
motility of the walls of the GIT
Submucosa
Layer of dense CT containing many
blood vessels and a plexus of
sympathetic nerves
Meissner’s
plexus
Composed of smooth muscle cells
spirally oriented into 2 sublayers
Tunica muscularis
circular
Internal
longitudinal
External
Between the layers is a second
sympathetic nerve plexus called
Auerbach’s plexus
coordinates the peristaltic contractions
Auerbach’s plexus
Outermost layer consisting of mesothelium which lines the abdominal cavity and covers the organs within it
Serosa
Main functions of the digestive tract’s lining epithelium:
Provide a selective permeable barrier
Facilitate the transport and digestion of food
Promote the absorption of the products of digestion
Produce hormones
Produce mucus for lubrication and protection
Serves as the entrance to the digestive tract
Oral Cavity
Has a lumen and surrounding coats or layers
Oral Cavity
Mucous membrane
Stratified squamous nonkeratinizing epithelium
Lamina propria, muscularis mucosa, submucosa layers
Palate
Pharynx
Oral Cavity
Orbicularis oris skeletal muscle and dense connective tissue
Lips
lined by stratified squamous nonkeratinizing
epithelium
Oral side
outer portion covered by typical thin skin; has hair
follicles, sweat glands, sebaceous glands
Skin side
red free edge of the lips; hairless very thin skin, transparent permitting the blood in the capillaries of the dermis to impart to it a red color
Vermilion border
Freely movable organ attached to the floor of the mouth and the hyoid bone
Tongue
Consists of interlacing bundles of skeletal muscles
Tongue
Lining epithelium of tunica mucosa is stratified squamous epithelium
Dorsal surface is covered by a relatively thick epithelium
Acinar glands
Secretes about 1.5-2 L of fluid /day
Pancreatic juice rich in bicarbonate ions and digestive enzymes (amylase, lipase, trypsinogen, proteases, nucleases, proelastases)
Duct of Wirsung
Exocrine
Transversely-oriented retroperitoneal organ extending from the “C” loop of the duodenum to the spleen
EXOCRINE PANCREAS
20 cm in length; 85-90 grams
Head, body and tail
EXOCRINE PANCREAS
Thin muscularis and absent submucosa
Cystic duct joins the common hepatic duct to form the common bile duct which empties into the 2nd portion of duodenum; opening is ampulla of Vater
Gallbladder
Hollow pear-shaped sacular organ lodged in the inferior surface of the right lobe of the liver
Gallbladder
10x4 cm; capacity of 40-70 ml bile
Fundus, body and neck
Gallbladder
Processing of amino acids, carbohydrates, lipids, and vitamins
Removal of microorganisms and toxins
Synthesis of plasma proteins
Detoxification and excretion into bile of endogenous waste products and pollutants
Functions of the Liver
Polygonal or hexagonal
Mass of liver parenchyma surrounded by the central vein
Portal triads in every corner of the hexagon
Liver: Classical Lobule
Largest gland in the body
1.5 kg in the adult
LIVER
Divided into right and left lobes
On its underside, blood vessels and bile ducts pass through its hilum or porta hepatis
LIVER
Dual blood supply
Receiving well oxygenated blood from the systemic circulation via the hepatic artery (25%)
Larger volume (75%) of poorly oxygenated blood coming from the intestinal tract via the portal vein
LIVER
Bile
Exocrine gland
Proteins and glucose
Endocrine gland
small triangular areas which are thickenings of CT which enclose
Portal triads
Glisson’s capsule
Stroma
Liver cells or hepatocytes which are arranged on hepatic cords or plates oriented radially from a central vein (branch of hepatic vein)
Parenchyma