Digestive System Flashcards
Secretions of the stomach include:
-chyme
-mucus
-intrinsic factor
-HCl acid
-Pepsinogen
chyme
ingested food plus stomach secretions
mucus
slimy fluid secreted by the mucous membranes; mucin + water; protects from pepsin
intrinsic factor
A substance produced by the mucosa of the stomach and intestines that is essential for the absorption of vitamin B12; bind with B12 for DNA synthesis
HCl acid
produced from parietal cells; protects from bacteria; stops carbohydrate digestion; converts pepsinogen to pepsin
pepsinogen
digestive enzyme in inactive form; produced from chief cells
Pepsin
digestive enzyme in active form present in gastric juice that begins the hydrolysis of proteins
process of hydrochloric acid production
1.In order to make CHL you need hydrogen and chloride
2.Co2 enters blood stream due to aerobic respiration
3.Co2 enters cell through diffusion and encounters/combines with water
4.Through carbonic + hydrase, they produce H2CO3
5.Remove one of the Hydrogen to make HCO3
6.Removed hydrogen uses ATP to take ion into duct through active transportation; while doing this we move a + charged potassium out
7.Potassium moves leaves via facilitated diffusion (non gated channel protein); potassium knocked out of cell and into concentrated gradient
What are the 3 phases of digestion?
Cephalic
Gastric
Intestinal
cephalic phase of digestion
Smell, sight, thought or initial taste of food activates neural centres; medulla oblongata starts process of secretion; preganglionic; gastrin is a secretary hormone used to produce HCl and pepsin
gastric phase
distention of the stomach wall that stimulates parasympathetic reflex
-stimulates further secretions
-stimulates local reflexes
Intestinal phase of digestion
- sensory input to medulla from duodenum inhibits motor input from medulla to stomach stopping secretion of pepsin and HCl
- local reflexes inhibit gastric secretions
- secretin, GIP and cholycstekinin produced by duodenum inhibit gastric secretion in stomach
What does secretin, gastric inhibitory polypeptide and cholecystokinin all do?
Inhibit stomach secretions
Secretin function
production of bile in liver and release of pancreatic juice
polypeptide function
release of bile from gall bladder