Digestive Enzymes & Their Actions

Question 1

Salivary alpha amylase

Answer 1

Site of secretion: Mouth
Preferred Substrate (s): alpha (1-4) bonds in starch, dextrins
Primary site of Action: Mount & Stomach

Question 2

Lingual lipase

Answer 2

Site of secretion: Mouth
Preferred Substrate (s): Triacylglycerol - composed of 3 FAs esterified to a glycerol
Primary site of Action: Mount & Stomach

This enzyme hydrolyzes TGs primarly after food has been swallowed & is in the stomach. Activity is most helpful in infants enhancing digestion of TGs in milk.

This enzymes activity diminishes with age (34)

Question 3

Pepsinogen/Pepsin

Answer 3

Site of secretion: Stomach
Preferred Substrate (s): Carboxyl end of phe, tyr, trp, met, leu, gluu, asp*
Primary site of Action: Stomach

Question 4

Gastric lipase

Answer 4

Site of secretion: Stomach
Preferred Substrate (s): Triacylglycerol (mostly medium chain)
Primary site of Action: Stomach

Question 5

Trypsinogen/trypsin

Answer 5

Site of secretion: Pancreas
Preferred Substrate (s): Carboxyl end of lys, arg*
Primary site of Action: Small Intestine

Question 6

Chymotrypsinogen/chymotrypsin

Answer 6

Site of secretion: Pancreas
Preferred Substrate (s): Carboxyl end of phe, tyr, trp, met, asn, his*
Primary site of Action: Small Intestine

Question 7

Procarboxypeptidase / carboxypeptidase A

Answer 7

Site of secretion: Pancreas
Preferred Substrate (s): C-terminal neutral amino acids
Primary site of Action: Small Intestine

Question 8

Carboxypeptidase B

Answer 8

Site of secretion: Pancreas
Preferred Substrate (s): C-terminal basic amino acids
Primary site of Action: Small Intestine

Question 9

Pancreatic alpha-amylase

Answer 9

Site of Secretion: Pancreas
Preferred Substrate (s): alpha (1-4) bonds, in starch, maltotriose
Primary Site of Action: Small Instestine

Question 10

Pancreatic lipase and colipase

Answer 10

Site of Secretion: Pancreas
Preferred Substrate (s): Triacyglycerol
Primary Site of Action: Small intestine

Question 11

Phopholipase

Answer 11

Site of Secretion: Pancreas
Preferred Substrate (s): Lecithin and other phospholipids
Primary Site of Action: SI

Question 12

Phopholipase

Answer 12

Site of Secretion: Pancreas
Preferred Substrate (s): Lecithin and other phospholipids
Primary Site of Action: SI

Question 13

Cholesterol esterase

Answer 13

Site of Secretion: Pancreas
Preferred Substrate (s): Cholesterol esters
Primary Site of Action: SI

Question 14

Amino peptidases

Answer 14

Site of Secretion: Small Intestine
Preferred Substrate (s): N-terminal amino acids
Primary Site of Action: SI

Question 15

Dipeptidases

Answer 15

Site of Secretion: Small intestine
Preferred Substrate (s): Dipeptides
Primary Site of Action: Small intestine

Question 16

Disaccharidases

Answer 16

Site of Secretion: small intestine
Preferred Substrate (s): N?A
Primary Site of Action: SI

Question 17

Sucrase

Answer 17

Site of Secretion:
Preferred Substrate (s): Sucrose
Primary Site of Action:

Question 18

alpha-glucosidase

Answer 18

Site of Secretion:
Preferred Substrate (s): Maltose
Primary Site of Action:

Question 19

Lactase

Answer 19

Site of Secretion:
Preferred Substrate (s): lactose
Primary Site of Action: