Differentiating Anemias Flashcards

1
Q

Fe deficiency?

A

Microcytic, hypochromic

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2
Q

Anemia of chronic disease?

A

Initially nonhemolytic, normocytic–progresses to microcytic, hypochromic

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3
Q

Hereditary spherocytosis?

A

Intrinsic hemolytic, normocytic anemia (extravascular)

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4
Q

Thalassemias?

A

Microcytic, hypochromic

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5
Q

Lead poisoning?

A

Microcytic, hypochromic

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6
Q

Folate deficiency?

A

Macrocytic, megaloblastic

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7
Q

Microangiopathic such as DIC, TTP, HUS, HELLP?

A

Extrinsic hemolytic, normocytic anemia (intravascular)

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8
Q

Sideroblastic anemia?

A

Microcytic, hypochromic

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9
Q

B12 deficiency?

A

Macrocytic, megaloblastic

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10
Q

Aplastic anemia?

A

Nonhemolytic, normocytic

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11
Q

G6PD?

A

Intrinsic hemolytic, normocytic (intravascular/extravascular)

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12
Q

Pyruvate kinase?

A

Intrinsic hemolytic, normocytic (extravascular)

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13
Q

Chronic kidney disease?

A

Nonhemolytic, normocytic

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14
Q

HbC disease?

A

Intrinsic hemolytic, normocytic (extravascular)

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15
Q

Prosthetic heart valve, aortic stenosis?

A

Macroangiopathic–extrinsic hemolytic, normocytic anemia

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16
Q

Orotic aciduria?

A

Macrocytic, megaloblastic

17
Q

Sickle cell?

A

Intrinsic hemolytic, normocytic (extravascular)

18
Q

Aplastic anemia–B19?

A

Nonhemolytic, normocytic

19
Q

Malaria, babesia?

A

Extrinsic hemolytic, normocytic (intravascular)

20
Q

Paroxysmal nocturnal hemoglobinuria?

A

Intrinsic hemolytic, normocytic (intravascular)

21
Q

Warm agglutinin (IgG) disease?

A

Extrinsic hemolytic, normocytic (intravascular)

22
Q

Cold agglutinin (IgM) disease?

A

Extrinsic hemolytic, normocytic (intravascular)

23
Q

Intravascular anemias?

A

1) PNH
2) G6PD deficiency
3) All extrinsic anemias (expect IgG immune anemia)

24
Q

Extravascular anemias?

A

1) Hereditary spherocytosis
2) PK deficiency
3) Sickle cell
4) HbC
5) IgG immune anemia