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Hem/Onc > Blood Cells > Flashcards

Blood Cells Flashcards

1
Q

Lifespan of RBCs?

A

120 days

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2
Q

Lifespan of neutrophils?

A

6-10 hours before migrating (majority of neuts found in bone)

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3
Q

Lifespan of platelets?

A

8-10 days

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4
Q

Source of energy for RBCs?

A

Glucose (90% glycolysis, 10% HMP shunt)

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5
Q

Erythrocytosis?

A

Polycythemia

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6
Q

Anisocytosis?

A

Varying sizes

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7
Q

Poikilocytosis?

A

Varying shapes

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8
Q

1/3 of platelets stored in this organ.

A

Spleen

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9
Q

Dense granules of platelets?

A

ADP, Ca

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10
Q

Alpha granules of platelets?

A

vWF, fibrinogen

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11
Q

WBC differential from highest to lowest?

A

Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils

Neutrophils Like Making Everything Better

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12
Q

Small more numerous specific granules in neuts contain?

A

Alk phos, collagenase, lysozyme, lactoferrin

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13
Q

Larger less numerous azurophilic granules (lysosomes) in neuts contain?

A

Acid phos, peroxidase, B-glucuronidase

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14
Q

Frosted glass cytoplasm?

A

Monocyte

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15
Q

Activated by IFN-g?

A

Macrophage

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16
Q

Functions via MHC-II?

A

Macrophage, dendritic cells, B cells

17
Q

CD14?

A

Macrophage

18
Q

CD19 and CD20?

19
Q

CD3?

20
Q

What do eosinophils release?

A

Histaminase and arylsulfatase (helps limit reaction following mast cell degranulation)

21
Q

Causes of eosinophilia?

A

Neoplastic, Asthma, Allergic processes, Collagen vascular dz, Parasites (NAACP)

22
Q

What do basophils release?

A

Heparin, histamine, leukotrienes (LTD4)

23
Q

What do mast cells release?

A

Heparin, histamine, eosinophil chemotactic factors

24
Q

Called Langerhans cells in skin?

A

Dendritic cells

25
Q

Abundant RER?

A

Plasma cell

26
Q

CD28?

A

Costimulatory molecule necessary for T-cell activation

Hem/Onc (3 decks)

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