dif Flashcards
Depression - sleep
Sleep disturbances in sleep stages: 1. decreased slow wave sleep
2. decreased REM latency 3. increased REM early in sleep cycle 4. increased total REM sleep 5. Repeated nightime awakening 6. Early-morning wakening (terminal insomnia)
Narcolepsy is caused by
decreased hypocretin (orexin) production in LATERAL hypothalamus strong genetic component
intermittent explosive disorder?
like antisocial but without history of conduct disorder or other fearures of antisocial
disulfiram vs naltrexone vs acamprosate as treatment of alcoholism
naltrexone –> to reduce craving (in active drinkers)
disulfiram –> in abstinent patients (2nd line)
acamprosate –> abstinent patients
Metabolic effects of the 2nd generation antiphsycotics - highest risk drugs / how to monitor
- Clozapine 2. Olanzapine
Baseline + regular follow-up: BMI, fastign glucose + lipids, BP, waist circumference (at 3 months and then annually)
- more frequent if DM or gained more than 5% of initial weight
hoarding disaster?
distinct from OCD
- accumulation of a large number of possessions that may clutter living areas to the point that they are usuable –> distress when attempting to discard possessions
interpersonal psychotherapy - indications / features
depression
- links symptoms to current relationship conflicts + interpersonal skill deficits
supportive psychotherapy - indications / features
- lower functioning, psychotic disorders
- patients in crisis
- maintains hope, provide encouragement
reinforces coping skills, adaptive defenses
psychodynamic psychotherapy - indications / features
- higher functioning personality disorders - builds insight into unconscious conflicts + past relationships uses transference breaks down maladaptive defenses
motivational interviewing - indications / features
substance use disorders
- nonjudgmental, acknowledges ambivalence + resistance
enhances intrinsic motivation to change
dialectical behavioral therapy - indications / features
borderline personality disorder
- improves emotion regulation, distress tolerance mindfulness
decreases self harm, build skills
biofeedback - indications / features
- prominent physical symptoms
pain disorders - improves control over physiological reactions to emotional stressors
start SSRI for Major depression - when to stop them
if single episode of major depression –> continue for additional 6 months following acute response to reduce the risk of relapse
with chronic, recurrent or severe episodes –> 1-3 years
medications that decreases lithium levels
theophylline
K+ sparing diuretics
Marchiafava-Bgnami disease
dementia, motor dysfunction, dyrsarthria
- severe damage to the corpus callosum and surrounding white matter due to chronic alcohol use disorder and malnutrition
Hoover sign
impaired flexion/extension strength of the hip with intact extension on contralateral hip flexion –> incompatible with known nerve pathways -> maybe conversion