Diazepam Flashcards
1
Q
Class of diazepam
A
Benzodiazepines
2
Q
How does diazepam lead to hyperpolarisation
A
+ affinity of GABA to GABAa receptor —> post-synaptic Cl- channels open —> +Cl-
3
Q
Indications of diazepam
A
- anxiety
- insomnia
- spasm
4
Q
Contraindications for diazepam
A
- Myasthenia gravis
- depression
- neuromuscular weakness
- acute pulm insufficiency
- pregnancy
5
Q
Side effects of diazepam
A
- hypotension
- dependence
6
Q
Diazepam is mostly excreted via
A
Urine
