Diastolic Function

Question 1

Diastole

Answer 1

A phase of the heart cycle where the chambers relax and fill with blood under low pressure

Question 2

Diastole is the interval from

Answer 2

AV closure to MV closure

Question 3

What does the relaxation phase of ventricular filing include

Answer 3

IVRT and early phase of ventricular filling

Question 4

Define compliance

Answer 4

Sv/Dp

Question 5

Compliance is the inverse to

Answer 5

Stiffness

Question 6

Stiffness is the

Answer 6

Change in pressure / change in volume

Question 7

Filling pressures include

Answer 7

LV EDP and mean LA pressure

Question 8

LVEDP reflects what

Answer 8

ventricular pressure after filling is complete

Question 9

Mean LA pressure is the

Answer 9

Average pressure during the filling period in the LA

Question 10

What are the 4 phases of diastole

Answer 10

IVRT
Early phase
Diastasis
Late phase

Question 11

IVRT is when there is

Answer 11

No change in ventricle volume but pressure in ventricle is falling

Question 12

Early phase is

Answer 12

Rapid filling of the LV

Question 13

Diastasis is when the

Answer 13

Pressures equalize between LV and LA

Question 14

Late phase is when the

Answer 14

Atria contract and push the rest through

Question 15

Late phase is also called the

Answer 15

“Atrial Kick”

Question 16

Valves are

Answer 16

Passive structures

Question 17

IVRT is the period

Answer 17

Between AV closure and MV opening

Question 18

Once LV pressure falls below LA pressure what happens

Answer 18

MV will open and then rapid filling phase begins

Question 19

IVRT is influenced by

Answer 19

Conduction abnormalities or conduction mechanics
Loading conditions
Age

Question 20

What are loading conditions

Answer 20

Preload

LAP

Question 21

Why does age effect the IVRT

Answer 21

Relaxation takes longer in older adults

Question 22

What is the normal timing for IVRT

Answer 22

50-100 ms

Question 23

Early rapid filling is the period between

Answer 23

MV opening and diastasis

Question 24

What are the properties of ventricular relaxation that causes blood to be effectively sucked from LA to the LV

Answer 24

Elastic recoil properties

Question 25

As the LV fills what happens

Answer 25

The LA is emptying as a result of the LA pressure and volume decreases

Question 26

What is the deceleration time

Answer 26

LA-LV pressure gradient begins to fall leading to a slowdown if blood entering the LV

Question 27

Rapid filling phase is influenced by

Answer 27

Rate of LV relaxation
Elastic recoil of the ventricle
Chamber compliance
LAP

Question 28

What contributes to 70-80% if total diastolic filling

Answer 28

Early filling

Question 29

What is the normal time for the early filling phase to occur

Answer 29

150-200 ms

Question 30

Diastasis is when the

Answer 30

LV and LA pressures are almost equal