Diastolic Function Flashcards
Diastole
A phase of the heart cycle where the chambers relax and fill with blood under low pressure
Diastole is the interval from
AV closure to MV closure
What does the relaxation phase of ventricular filing include
IVRT and early phase of ventricular filling
Define compliance
Sv/Dp
Compliance is the inverse to
Stiffness
Stiffness is the
Change in pressure / change in volume
Filling pressures include
LV EDP and mean LA pressure
LVEDP reflects what
ventricular pressure after filling is complete
Mean LA pressure is the
Average pressure during the filling period in the LA
What are the 4 phases of diastole
IVRT
Early phase
Diastasis
Late phase
IVRT is when there is
No change in ventricle volume but pressure in ventricle is falling
Early phase is
Rapid filling of the LV
Diastasis is when the
Pressures equalize between LV and LA
Late phase is when the
Atria contract and push the rest through
Late phase is also called the
“Atrial Kick”
Valves are
Passive structures
IVRT is the period
Between AV closure and MV opening
Once LV pressure falls below LA pressure what happens
MV will open and then rapid filling phase begins
IVRT is influenced by
Conduction abnormalities or conduction mechanics
Loading conditions
Age
What are loading conditions
Preload
LAP
Why does age effect the IVRT
Relaxation takes longer in older adults
What is the normal timing for IVRT
50-100 ms
Early rapid filling is the period between
MV opening and diastasis
What are the properties of ventricular relaxation that causes blood to be effectively sucked from LA to the LV
Elastic recoil properties
As the LV fills what happens
The LA is emptying as a result of the LA pressure and volume decreases
What is the deceleration time
LA-LV pressure gradient begins to fall leading to a slowdown if blood entering the LV
Rapid filling phase is influenced by
Rate of LV relaxation
Elastic recoil of the ventricle
Chamber compliance
LAP
What contributes to 70-80% if total diastolic filling
Early filling
What is the normal time for the early filling phase to occur
150-200 ms
Diastasis is when the
LV and LA pressures are almost equal
