Diarrhea Flashcards
Definition
Abnormal increase in stool frequency or liquidity
• Abnormal > 3 BM/day
Acute DIA
Less than 4 weeks
F&E replacement
Dietary intervention
OTC meds
Chronic DIA
More than 4 weeks
Refer
Viral Gastroenteritis
Contaminated food/water
Rotavirus
Norovirus
Bacterical Gastroenteritis
Can treat
Contaminated food
Traveler’s diarrhea
Protazoal
Refer, need antibiotics
Giardia
Cryptosporidium
Drug-induced
Antibacterial agents
Cytotoxic agents
Laxatives
Mg products
AIDS-associated
Refer
Food-induced
Food allergy
Excessively fatty or spicy
High amount of roughage
Lactase deficiency
Complications
• Fluid and electrolyte imbalance dehydration
Mild Dehydration
3-5% wt. loss <3 unformed stools/day Mild thirst Slight dry mouth Slight UO Afebrile/low-grade fever Normal BP *Self-treat
Mod Dehydration
6-9% wt. loss 4-5 unformed stools/day Sunken eyes/fonatanelle Dry mouth UO/ tearing Restlessness Fever >101 Orthostatic BP/pulse *Self-treat
Severe Dehydration
10% wt. loss or more 6-9 unformed stools/day Rapid, thready pulse Cyanosis Cold extremities Rapid breathing Lethargy and dizziness Fever > 101 Low BP Severe abdominal pain *Refer
who should be referred?
- Chronic medical condition(s)
- Pregnancy
- 65 years of age
- Same or worsening after 48 hours of onset
Treatment Goals
- Prevent or correct fluid and electrolyte loss and acid-base disturbances
- Relieve symptoms
- Identify and treat cause
- Prevent acute morbidity and mortality
General Treatment Approaches
Fluid electrolyte balanceDietOTC meds
F&E balance
For mild to moderate diarrhea
Carbohydrates- facilitate Na and H2O absorption
Electrolytes
Carbs
Glucose
Dextrose
Rice syrup solid
Crystalline fructose
Electrolytes
Sodium Chloride Citrate Potassium *Pedialyte is only fluid with an osmolarity 300 will make water go into the GI tract – BAD
General Dosing: Pedialyte
• 1-2oz per lb. of body wt over 2-4 hours
- 1 tsp q10min x 30min, if tolerated
- 1 tbsp q20min x 1hr, if tolerated
- 2 tbsp q30min x 1hr, if tolerated
- 4-6oz q 3-4hrs up to 1-2L/day
Pedialyte storage
shelf life is 48 hours, throw away after
Pedialyte adult dosing
: ½ to 1 cup after each loose BM
Diet
– if oral intake does not worsen diarrhea
Diet: infants and children
Breast milk, formula, or cow’s milk is OK
Diet: foods to eat
Carbohydrate-rich (yogurt, lean meats, fruits, vegetables)
BRATTY Diet not enough calories
Diet: Avoid
Fatty foods
Foods rich in simple sugars
Spicy foods
Caffeine
BRAT Diet
BananasRiceApple sauceToastTeaYogurt
Prevention
- Isolate for at least 24-48 hours
- Wash hands
- Sterilizing techniques
- Strict food handling practices
- Sanitation and good hygiene
- Bismuth Subsalicylate as prophylaxis for Traveler’s diarrhea
Loperamide dosing
• Imodium AD
2mg/cap
1mg/5mL
• Imodium Advanced
Loperamide - 2mg
Simethacone -125mg
Loperamide Dosage and DOA
- 4mg initially, then 2mg after each loose BM (adults)
- 1/2 dose in children
- Max: 16 mg/day
- Children’s max depends on age and wt.
- DOA: 48 hours
Loperamide Indication
- Acute, nonspecific diarrhea
- Traveler’s diarrhea
- Chronic diarrhea associated with IBS
Loperamide MOA
• Slows intestinal motility
Loperamide Effects
- decreased daily fecal volume
- increased viscosity
- Bulk volume
- decreased F&E loss
Loperamide AE
- decreased CNS poorly
- Dizziness
- Constipation
Loperamide Contras/warnings
- <6
- Febrile
- Blood/mucous in the stool
- Geriatrics (CNS depression and fatigue)
Bismuth Dosage and DOA
- 2 tab qh
- 30mL q30-60min
- Max: 16 tab/day or 240mL/day
- Max: 8 doses/day
- Labeled for 12 and up
- DOA: 48 hours
Bismuth indications
• Mild, nonspecific diarrhea • Traveler’s Diarrhea *2tab or 1fl oz. QID • Indigestion • H. pylori
Bismuth MOA
- Coats the stomach
* Acts like aspirin
Bismuth Effects
- decrease frequency of unformed stools
- increased stool consistency
- Relieve cramping
- decreased n&v
Bismuth AE
- In combo with other salicylates
- Tinnitus
- Reye’s Syndrome
- Black staining of the stool/tongue
Bismuth Contras/warnings
• Pregnancy • Lactation • Aids due to neurotoxicity (encephalopathy) • Antiplatelet effect • Geriatrics –limit use *Tinnitus or CNS SE • Anticoagulants
Bismuth interactions: Increased effects
- Warfarin
- Valproic acid
- Methotexate
Bismuth interactions: decreased effects
• Probenecid
Bismuth effects: decreased absorption
- Tetracycline
* Fluoroquinolone
Helidac
treats duodenal ulcers • 2 chewable bismuth subsalicylate 262.4 mg • 1 metronidazole 250mg • 1 tetracycline 500mg o dose above QID x 14days
Lactobacillus
- Not considered effective as an anti-diarrheal therapy by FDA
- Dosed 3-4times/day
Acidophilus Tabs
• Refrigerate after opening
Align
• Once a day dosing
Lil Critters
• BID dosing = 10 servings of yogurt
Saccaromyces boularii lyo
- Yeast culture – SE vaginal yeast infection
- Used in 3 months and up
- Florator Kids for 2 months and up