Diagnostics Flashcards
When would you use light’s criteria?
Use if protein level of pleural fluid is between 25-35g/L
Protein level in EXUDATIVE effusions
Protein > 30g/L
Protein level in TRANSUDATIVE effusions
Protein < 30g/L
Haemothorax
Pleural Fluid Haematocrit > half peripheral blood haematocrit
Empyema
Perform a diagnostic tap for pleural effusions associated with sepsis of pneumonia
Purulent or turbid/cloudy pleural aspirate
OR
pH < 7.2
Rx -> wide bore chest drain
What does serum Beta D Glucan test for?
Invasive or disseminated fungal infection
False +ve if contaminated specimens from beta D glucan producing bacteria (e.g. strep pneumoniae, pseudomonas) or fungal contaminants in Abx (co-amoxiclav and tazocin)
Light’s Criteria:
An exudate is likely if at least one of…
- fluid protein/ serum protein > 0.5
- fluid LDH/ serum LDH > 0.6
- fluid LDH > 2/3 upper limit normal serum LDH
Causes of upper lobe predominant pulmonary fibrosis
- CF
- Sarcoidosis
- Langerhans cell histiocytosis
- TB
- Silicosis
- ABPA
- Chronic Hypersensitivity Pneumonitis
- Histoplasmosis
- Drugs e.g. chemo
- Ankylosing Spondylitis
- Progressive Massive Fibrosis (assoc. pneumoconioses)
- Pleuroparenchymal fibroelastosis
Moderate Acute Asthma
- PEFR 50-75%
- normal speech
- RR < 25/ min
- HR < 110 bpm
Sever Acute Asthma
- PEFR 33-55%
- incomplete sentences
- RR > 25/min
- HR > 110bpm
Life-threatening Acute Asthma
- PEFR < 33%
- Sats < 92%
- silent chest, cyanosis, weak respiratory effort
- bradycardia, dysrhythmia, hypotension
- exhaustion, confusion, coma
Pulmonary Hypertension (PAH)
Sustained elevation in mean pulmonary arterial pressure > 25 mmHg at rest
Group 1: PAH
- idiopathic i.e. primary PAH
- familial
- assoc. collagen vascular dx, CHD with systemic to pulmonary shunts, HIV, drugs/toxins, sickle cell dx
- persistent PAH of the newborn
Group 2: PAH with left heart dx
- e.g. LVSD, mitral stenosis, mitral regurgitation
Group 3: PAH secondary to lung dx/hypoxia
- COPD
- ILD
- OSA
- High altitude