Diagnostic Criteria Flashcards

1
Q

JONES Criteria

A

RHEUMATIC FEVER

2 major or 1 major + 2 minor

J - migratory polyarthritis 
O - heart (pericarditis, CHF, valve disease) 
N - subQ nodules 
E - erythema marginatum 
S - S. chorea 
  • fever
  • elev ESR
  • polyarthralgia
  • prior rheumatic fever
  • prolonged PR
  • evid preceding strep infection
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2
Q

Duke Criteria

A

INFECTIOUS ENDOCARDITIS

2 major or 1 major 3 minor or 5 minor

  • Sustained bacteremia of known endocarditis organism
  • New regurg or abnormality seen on valve imaging
  • fever
  • predisposing condition - abnormal valve
  • vascular signs (PE, janeway lesions, ICH)
  • immune signs (Osler nodes, glomerularnephritis, RF, roth spots)
  • Pos blood cx - not known organism
  • Pos echo - not major criteria
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3
Q

Definition of Hypertensive Urgency / Emergency

A

Sys > 220

OR diastolic > 120

EMER = signs end organ damage (altered, papilledema, renal failure, hematuria, USA, MI, CHF, pulmonary edema)

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4
Q

SIRS

A

2+ of following

  • Temp >38 or < 36
  • Hyperventilation >20 or PaCO2 < 32
  • Tachy > 90
  • WBC > 12 or <4 or >10% bands
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5
Q

Sepsis

Septic Shock

A

Sepsis - SIRS + source of infection

Shock - sepsis + hypotension despite adequate fluids

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6
Q

Indications for Home O2 Requirement

A

SaO2 < 88%

PaO2 < 55

PaO2 55-59 but evidence for pulmonate or polycythemia

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7
Q

Light’s Criteria

A

EXUDATIVE IF …

  • Pleural protein / serum protein > .5
  • Pleural LDH / serum LDH > .6
  • Pleural LDH > 2/3 ULN for serum LDH
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8
Q

ARDS

A

BERLIN CRITERIA

Bilat infiltrates on CXR (white out)

Pulmonary edema not explained by CHF or fluid overload (wedge pressure < 18)

PaO2/FiO2 = 100 - 300 (100 being more severe)
***AKA hypoxemia refractory to oxygen therapy

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9
Q

Pulmonary HTN

A

Mean pulmonary artery pressure > 25 mmHg

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10
Q

Well’s Criteria

A

Sx or signs DVT - 3 pt
Alt diagnosis less likely - 3 pt
HR > 100 - 1.5 pt
Immobilization for 3 days or surgical in 4 wks - 1.5 pt
Previous DVT or PE - 1.5 pt
Hemoptysis - 1 pt
Malignancy (pall or therapy in last 6 mo) - 1 pt

Score > 4 means PE likely

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11
Q

SAAG

A

Serum Ascites Albumin Gradient

Serum albumin - ascites albumin

If > 1.1 then portal HTN likely

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12
Q

Indications for Paracentesis of Ascites

A
  • New onset ascites
  • Worsening ascites
  • Suspected SBP
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13
Q

SBP Dx

A

WBC > 500 or PMN > 250 in ascites fluid

Cx - can be negative

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14
Q

Child’s Score

A

Ascites - none/moderate/severe

Bili - <2/2-3/>3

Encephalopathy - none/moderate/severe

INR - <1.7 / 1.7-2.3 / > 2.3

Albumin - > 3.5 / 2.8 - 3.5 / < 2.8

A - 5 to 6 pts
B - 7 to 9 pts
C - 10 to 15 pts

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15
Q

PBC v. PSC v. AIH

A

Primary Biliary Cirrhosis - AI, women, AMA

Primary Sclerosing Cholangitis - UC

Autoimmune Heptatitis - anti smooth muscle and anti liver kidney

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16
Q

Ranson Criteria

A

Pancreatitis Prognosis

ADMISSION (“ga law”)

  • Glucose > 200
  • Age > 55
  • LHD > 350
  • AST > 250
  • WBC > 16,000
48 HOURS ("c hobbs")
Ca < 8 
HCT dec >10% 
PaO2 < 60 
BUN inc > 8 
Base Deficit > 4 
Fluid sequestration >  6 L 

Mortality approaches 100% if 7+ criteria

17
Q

DM Dx

A

2 fasting > 125

Single random glucose > 200 + sx

2 hr post-prandial > 200 (give 75 g load)

HgbA1c > 6.5%

18
Q

Criteria for Brain Death

A

Irreversible absence of brain or brainstem function (apnea, no pupil, doll’s eyes, etc)

No drug or metabolic intoxication present

Body temp > 32

Clinical evidence or imaging to provide cause of brain death

Repeat exam or repeat EEG (isoelectric)

19
Q

Criteria for Brain Death

A

Irreversible absence of brain or brainstem function (apnea, no pupil, doll’s eyes, etc)

No drug or metabolic intoxication present

Body temp > 32

Clinical evidence or imaging to provide cause of brain death

Repeat exam or repeat EEG (isoelectric)

20
Q

MS Dx

A

2 episodes of sx + evidence 2 white matter lesions

2 episodes of sx + 1 white matter lesion + oligoclonal bands in CSF

21
Q

SLE Dx

A

4/11 Sx

Rash (4) - malar, discoid, ulcers, photosensitive

Arthritis

Pericarditis, pleuritic

Heme - anemia, leukopenia, thrombocytopenia, etc

Renal - > .5 g/day protein

CNS - sz or psychosis

Anti DS DNA, false pos syphilis, anti-smith

Pos ANA

22
Q

What test is used for scleroderma dx?

A

Schirmer - filter paper to test lacrimal secretion

23
Q

RA Dx

A
  • inflammation of 3+ joints
  • sx for 6+ wks
  • Elev CRP and ESR
  • Pos RF or anti-CPP
  • Xrays showing erosion and peri-articular de-calcifications
24
Q

Polymyositis

A
  • Symm proximal muscle weakness
  • Elev CPK
  • EMG myopathy findings
  • Muscle biopsy showing myositis

***If rash then diagnosis is dermatomyositis

25
Q

Fibromyalgia

A

Widespread axial pain for 3+ mo

11/18 possible tender points

R/o RA, hypothyroid, Lyme, depression, ankylosing spondylitis, etc

26
Q

Various Vasculitis Dx

A

Giant Cell Temporal - temporal artery biopsy

Takayasu - arteriogram

Churg-Strauss - pANCA and eosinophilia

GPA - c-ANCA + lung biopsy, hematuria

PAN - pANCA, NO LUNG IINVOLVEMENT, biopsy of tissue or mesenteric angiography

27
Q

AKI

A

Increase in serum creatinine by ≥0.3 mg/dL within 48 hours

Increase in serum creatinine to ≥1.5 times baseline, which is known or presumed to have occurred within the prior seven days

Urine volume <0.5 mL/kg/hour for six hours

28
Q

MGUS v Mult Myeloma

A

MGUS

  • IgG spike < 3 g
  • < 10% plasma cells in bone marrow
  • Bence jones proteinuria < 1 g / 24 hrs
  • no end organ damage
MM 
- > 10% abnormal plasma cells in bone marrow + 1 of following ... 
1- M protein in serum 
2- M protein in urine 
3- lytic bone lesions on imaging
29
Q

CML v. True Leukomoid Reaction

A

Leukomoid

  • no splenomegaly
  • inc leukocyte alkaline phos
  • hx infection

CML

  • splenomegaly
  • dec leukocyte alkaline phos
  • no infection recently
30
Q

Polycythemia Vera

A

3 MAJOR or 2 MAJOR + 2 MINOR

Maj

  • RBC mass > 32 women, > 36 men
  • O2 sat > 92%
  • splenomegaly

Min

  • Platelets > 400
  • WBC > 12
  • Leuk alk phos > 100 w/o infection or fever
  • Vit B12 > 900
31
Q

Essential Thrombocytopenia

A

Platelets > 600,000

32
Q

Pos PPD by Population

A

Pos > 15 mm in normal patient

Pos > 10 mm if high-risk prison/immigrants/DM

Pos > 5 mm if HIV, steroid user, organ transplant, contact w/ someone w/ active Tb