Diagnostic (4th June 2024) Flashcards
Lipophilic
Ability of a chemical compound to dissolve in fats, oils, lipids and non polar solvents
Alpha decay
An atomic nucleus emits an alpha particle. The daughter is an atom with a mass number 4 less and an atomic number 2 less than the parent
Beta plus decay
AKA positron emission. A positron is emitted from the parent nucleus. The daughter has one less proton
Beta minus decay
A neutron is converted into a proton an an electron is emitted. The daughter has an atomic number that increases by one.
R constant
Remains constant independent of altitude, pressure or any other environmental variable
Magnetic field strength
B = µoI/2r
Electrical power
IV
Gibbs free energy for overall reaction
The Gibbs free energy change of the overall reaction for is the sum of the ΔG values of both steps
Mechanical work
work = Fdcos(θ), where F is the force applied, d is the distance over which the force is applied, and θ is the angle between the force applied and the direction of the object’s movement.
EM waves
Gamma
X-rays
UV rays
Visible light
IR
Microwaves
Radio (longest wavelength)
Mechanical power
a measurement of work/time (J/s, also known as watts). From the work-energy theorem, work = ΔKE = KEf – KEi. Thus, power can also be expressed as ΔKE/time. Remember also that KE = ½ mv2.
Imine
a carbon double bonded to a nitrogen atom
D,L configuration
The D, L designation describes the glyceraldehyde precursor in sugars, and amino acid functionality. It does not describe the absolute configuration.
pH
-log[H+]
Poiseuille’s Law
Flow = ΔPπr4 / 8Lη
Voltage Gradient
positive ions flow down voltage gradients from high voltage to low voltage
AND
extracellular concentration of sodium ions is greater than the intracellular concentration
Work done by system
The area under or inside the curve represents the product of the two variables on the axes. For fluid systems, Wby system = PΔV
Competitive inhibitor
A competitive inhibitor will increase the Km of a given reaction while leaving Vmax unchanged at high substrate concentrations. This is depicted in the figure.
Noncompetitive inhibitor
A noncompetitive inhibitor would lower Vmax but leave Km unchanged.
Restriction enzymes
A restriction enzyme is an enzyme that cuts DNA at or near specific recognition nucleotide sequences, known as restriction sites.
Type II restriction enzyme
Type II enzymes cleave within or at short specific distances from their recognition sites and often require magnesium.
Type I restriction enzyme
Type I enzymes cleave at sites remote from the recognition site; they require both ATP and S-adenosyl-L-methionine to function.
Type III restriction enzyme
Type III enzymes cleave at sites a short distance from their recognition sites and require ATP (but do not hydrolyze it). S-adenosyl-L-methionine increases the rate of this reaction, but is not required.
Type IV restriction enzyme
Type IV enzymes target modified (e.g. methylated, hydroxymethylated) DNA.
Conjugation
transfer of genetic material (plasmids) between bacterial cells by direct cell-to-cell contact or via a bridge-like connection between two cells. This process does not relate to thymidine kinase.