Diagnosis and Cellular Pathology Flashcards
Give four examples of Adaptive Processes.
Atrophy, Hypertrophy, Hyperplasia, Metaplasia
Two types of Cell Injury
Reversible; Irreversible
Define Stress.
Any stimulus or succession of stimuli of such magnitude that tend to disrupt the homeostasis of the organism; can cause injury
When adaptive capability is exceeded or in certain instances when adaptation is no longer possible due to severe stimulus, it leads to?
Cell Injury
type of cell death characterized by severe membrane injury and enzymatic degeneration
necrosis
regulated form of cell death, ex: renewal of skin cells
apoptosis
What is Homeostasis?
Cells are able to maintain normal structure and function in response to physiological demands
It could alter the normal steady state of cell or alter homeostasis of the body’s homeostasis
Injury
Two processes acquired during cell injury
- Cells may survive in a damage state and adapt to injury (Reversible Injury).
- Die or Cell Death (Irreversible Injury).
Father of Cellular Pathology
Rudolf Virchow
Put forward the concept that disease begins at the molecular and cellular level
Rudolf Virchow
What are the 11 Components of Description?
- Tissue
- Number
- Important Distribution
- Shape
- Color
- Size
- Pattern
- Consistency
- Special features
- Others such as odor
- Surface
What are the morphologic dx modifiers? Give examples each.
- Severity - mild, severe, moderate
- Duration - acute, chronic
- Distribution - focal, multifocal, locally extensive, diffuse
- Nature of Lesion - inflammatory, degeneration
- Organ prefix - osis, opathy, itis
3 steps useful in Veterinary Medicine
- Observe carefully.
- Describe completely.
- Diagnose confidently.
Define Biopsy.
Removal and examination of tissue from the living body in order to establish precise diagnosis.
It is a concise statement or conclusion concerning the nature, cause, and name of the disease.
Diagnosis
Differentiate morphological/lesion dx from differential dx.
Morphological dx is best on predominant lesion in the tissue while differential is a list of diagnosis that could account for the history, clinical signs, or lesions in the case.
diagnosis that names the specific cause
Etiologic dx
specific diagnosis which states the name of the disease
Disease dx or definitive dx
Differentiate morphological pathologists and clinical pathologists.
Morphological pathologists study morphologic manifestation of disease. Meanwhile, clinical pathologists specialize through laboratory analysis of disease.
Descriptions in Gross Pathology (6)
- No interpretations should appear in the description of lesion.
- Description should be concise.
- Grammatically correct.
- Anatomically accurate.
- Avoid making description based on frequency diagnosis.
