DIAGNOSIS Flashcards
Diagnostic criteria
two abnormal test results are required from either the
same sample or two separate samples unless unequivocal symptoms of hyperglycemia exist, such as polydipsia, polyuria, and
polyphagia
Tests for detecting and confirming DM
A1c, FPG, OGTT
Fasting plasma glucose levels for normal, IFG and diabetes (ADA)
Normal < 100mg/dl or <5.6mmol/l
IFG (prediabetes) 100–125mg/dl or 5.6–6.9mmol/l
Diabetes ≥ 126mg/dl or ≥ 7.0mmol/l
OGTT values for glucose levels (ADA)
Normal < 140mg/dl or < 7.8mmol/l
IGT (prediabetes) 140–199mg/dl or 7.8–11.0mmol/l
Diabetes ≥ 200mg/dl or ≥ 11.1mmol/l
ADA diagnosis for diabetes using A1c
greater or equal to 6.5 or 48mmol/mol Hgb
ADA diagnosis for diabetes using fasting plasma glucose
greater or equal to 126mg/dl or 7.0 mmol/l
ADA diagnosis for diabetes using OGTT
greater or equal to 200mg/dl or 11.1 mmol/l
ADA diagnosis for diabetes using random blood sugar or plasma glucose concentration
greater or equal to 200mg/dl or 11.1mmol/l
Diagnosis of GDM using fasting plasma glucose (WHO)
5.6mmol/l or more
Diagnosis of GDM using 2-h plasma glucose level (WHO)
7.8mmol/l or more
what is fasting as used in fasting plasma glucose
no caloric intake for at least 8 hours
What is the glucose load used for OGTT
Equivalent of 75g anhydrous glucose dissolve in water
At which gestational age is screening for GDM done
24 to 28 weeks
Methods of GDM screening
- One step strategy using a fasting 75g OGTT
- Two step strategy starting with a non fasting 50g glucose load test
Steps in the two step strategy for GDM screening
- Non-fasting 50g glucose test
- Fasting 100g glucose load