Diagnoses II Flashcards
Name 3 pervasive developmental disorders
Pervasive developmental disorders (axis I)
- Autism spectrum (includes old Asperger’s)
- Rett’s d/o
- Childhood disintegrative d/o
Autism
(a) Age of onset
(b) prevalence
(c) rate of comorbid MR
(d) gender difference
Autism (axis I pervasive developmental d/o)
(a) Almost always have symptoms before 3 years old
(b) 1/150 births (.6%)
(c) 70% have comorbid MR
(d) 3-4:1 boys:girls
Symptoms of Autism
-how many to qualify for dx
Autism: 6+ total symptoms
Social interaction impairment (2+)
- impairment of nonverbal behavior (poor eye contact)
- failure to develop peer relationships
- lack of spontaneous seeking to share enjoyment
Social Communication problems (1+)
- delay or lack of spoken language
- stereotyped use of language
- lack of varied or spontaneous play
Restrictive Behavior/Interests (1+)
- intense preoccupation w/ object
- inflexible adherence to rules
- repetitive motor mov’ts
What is Rett’s disorder?
(a) population
(b) age of onset
(c) main symptoms
(d) prognosis
Rett’s d/o = pervasive developmental d/o
(a) only in females: MCP2 gene on X chromosome
- thought to be lethal in utero for males
(b) Normal development in first 5 mo. 5-38 mo = deceleration causing lifelong impairment
(c) decrease in head circumference growth velocity during 5-38 months
- loss of previously acquired hand skills => stereotyped hand mov’t
- impaired language, psychomotor retardation, gait or trunk abnormal mov’ts
(d) cognitive development never progresses beyondt hat of first year of life
Childhood disintegrative d/o
(a) population
(b) age of onset
(c) symptoms
Childhood disintegrative d/o = pervasive developmental d/o
(a) Males 4:1
(b) Normal first 2 years, then onset before age 10
(c) Loss of previously acquired skill in 2+
1. language
2. social skills: bowel/bladder control, play, motor skills
2+ of the following
- impaired social interaction
- impaired use of language
- restricted, repetitive, and stereotyped behaviors and interests
What to rule out when assessing for developmental d/o
Rule out an organic cause!
- r/o vision problem, maternal health
- lab testing: chromosomal analysis, lead levels
Dx of MR
MR now called intellectual disability- have to have both:
subaverage intellectual functioning w/ IQ
Gender ratio of ID and possible explanation
- 5:1 M:F for ID
- Fragile X syndrome = most common inherited form of mental retardation (second overall) due to X chromosomal mutation
MR + obesity
Prader-Willi syndrome: MR, obesity, hypogonadism, almond-shaped eyes
-genetic cause of MR
Most common learning disorder
Reading disorder
4-10% of school-age children
Differentiate autism and asperger d/o
Both
- impairments in social interaction
- restricted or stereotyped interests and behaviors
Aspergers: no clinically sig delay in spoken or receptive language or cognitive development
-no delay in self-help skills or curiosity about environment
Contrast Rett d/o and Childhood disintegrative d/o
-both have high rates of EEG abnormality and seizure d/o
Rett d/o
-earlier onset (before 1st year)
Childhood disintegrative d/o
- head growth does not slow
- unusual hand movements are not present
Criteria for Tourette d/o
(a) more common in which gender
Tourette d/o = most severe tic d/o- multiple daily motor and 1+ vocal tics w/ onset before age 18
Describe types of
(a) motor tics
(b) vocal tics: coprolalia and echolalia
Tics
(a) motor tics- often involve face and head
ex: blinking eyes
(b) vocal tics often
- coprolalia = repetitive speaking of obscene words (uncommon in children)
- echolalia = exact repetition of words
Tourettes d/o
(a) more common in which gender
(b) peak age
(c) comorbidities
(d) neurochemial etiology
Tourettes d/o
(a) boys > girls
(b) peak in severity btwn 8-12, decreases w/ puberty
(c) high comorbidity w/ OCD (40%) and ADHD (50%)
(d) impaired regulate of dopamine in the caudate nucleus
Pharmacologic tx for tourettes
Atypical neuroleptics (risperidone)
Alpha-2 agonists = clonidine, guanfacine
What is selective mutism?
Girls > boys
Refusal to speak in certain situations for at least 1 month
ex: little girl will speak at home but not in school
Parents w/ anxiety d/o predispose their children to what?
Separation anxiety d/o
Differentiate the 3 anxiety disorders w/ identifiable stressor
Identifiable stressor of grave danger=> acute stress disorder vs. PTSD depending on timeline
- acute stress d/o: begins w/in 1 month of stressor, lasts less than 1 month
- PTSD begins anytime, lasts over 1 mo
Not life threatening identifiable stressor => adjustment d/o
-begins w/in 3 months, lasts less than 6 mo
Then free-floating anxiety, not fixed on a specific thing = GAD
Differentiate bereavement and grief
Bereavement- must be the loss of a loved one, while grief can be from anything (ex: divorce)
-pathological if > 1 yr or overtly psychotic
4 features of PTSD
PTSD: begins anytime, lasts > 1 mo
- re-experiencing (flashbacks, nightmares)
- avoidance of stimuli associated w/ trauma
- numbing of responsiveness (affect, detachment)
- increased arousal
Differentiate adjustment d/o and GAD
Adjustment d/o: due to non-life threatening stressor, begins w/in 3 month of and ends less than 6 months after stressor
- if it persists for 6 months after the stressor = GAD
- or can be chronic adjustment d/o if the stressor recurs or persists
Most effective tx for adjustment d/o
(a) gender disparity of adjustment d/o
Supportive therapy
(a) 2:1 F:M
GAD
(a) gender disparity
(b) comorbidity
(c) lifetime prevalence
(d) time requirement
(e) prognosis
Generalized anxiety d/o
(a) 2:1 F:M
(b) 50-90% have MDD, phobia, panic
(c) 45% lifetime prevalence
(d) lasts 6+ months
(e) 50% completely recover, 50% have chronic lifelong symptoms
Symptoms of GAD
GAD: excessive worry about daily events and activities
3+ associated symptoms
- restlessness, fatigue, irritability
- impaired concentration
- muscle tension, sleep disturbance
Treatment for GAD
(a) acute
(b) chronic
GAD tx
(a) acute = benzos
(b) chronic: psychotherapy + pharma: Buspirone, SSRI, Venlafaxine
Panic d/o
(a) prevalence
(b) most common comorbidity
(c) 2 requirements for diagnosis
Panic d/o
(a) 2-5%
(b) 40-80% comorbid MDD
(c) Spontaneous recurrent panic attacks w/ no obvious precipitant
- followed by 1 month of fear of panic attack, worry, change behavior
Tx for panic d/o
(a) acute- rule out what first?
(b) maintenance tx
Tx for panic d/o
(a) acute- rule out organic cause (ex: MI), then benzos
(b) maintenance- CBT + 8-12 months of SSRI (higher dose than for depression)
What are the most common mental disorders?
(a) time requirement
Specific phobias
(a) 6+ months if
Differentiate social phobia from agoraphobia
Agoraphobia = fear of being in a place where they can’t escape (ex: common w/ panic d/o)
=> avoidance of being in places or situations from which escape or help might be difficult
Social phobia = anxiety brought on by fear of embarassment