Diabetic Neuropathy & Foot Care Flashcards

1
Q

What is diabetic neuropathy?

A
  • Decreased sensation in stocking distribution
    • Sensory loss is patchy so must be tested in all areas with a 10g monofilament fibre
    • Swelling, instabilty and deformity
  • Absent ankle jerks
  • Neuopathic deformity such as Charcot joint, pes cavus. claw toes, loss of transverse arch, rocker bottom sole
    • Caused by loss of pain sensation, leading to increased mechanical stress and repeated joint injury
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2
Q

How is ischaemia tested in diabetics?

A
  • If foot pulses cannot be felt, use Doppler pressure measurement
  • Any evidence pf vascular disease or neuropathy, rasies risk of foot ulceration
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3
Q

How is diabetic ischaemia tested?

A
  • Education - daily foot inspection and wear comfortable shoes
  • Regular chiropody to remove callus as haemorrhage and tissue necrosis may occur, leading to ulceration
  • Treat fungal infections
  • Surgery - angioplasty, stents, balloons and recanalisation
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4
Q

How do foot ulceration present?

A
  • Typically painless
  • Punched out ulcer
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5
Q

What can foot ulceration lead to?

A
  • Cellulitis
  • Abscess
  • Osteomyelitis
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6
Q

How is foot ulceration managed?

A
  • Regular chiropody
  • Bed rest and therapeutic shoes
  • Bisphosphonates may help
  • For cellulitis - admit for IV antibiotics (benzylpenicllin and flucloxacillin and metronidazole
  • IV insulin may improve healing
  • Get surgical help early
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7
Q

What are the indications for surgery in foot ulceration?

A
  • Abscess
  • Deep infection
  • Spreading anaerobic infection
  • Gangrene
  • Rest pain
  • Suppurative arthritis
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8
Q

How are diabetic neuropathies treated?

A
  • Paracetamol
  • Tricyclics –> Amitriptyline
  • Duloxetine, Gabapentin, Pregabalin
  • Opiates
  • Immunosupression may help if sudden or severe
    • Corticosteroids
    • IV immunoglobulin
    • Ciclosporin
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9
Q

What is Amyotrophy?

A

Painful wasting of quadraceps and other pelvifemoral muscles

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10
Q

How does autonomic neuropathy present?

A
  • Postural hypotension
  • Decreased cerebrovascular autoregulation
  • Loss of respiratory sinus arrythmia (vagal neuropathy)
  • Gastroparesis
  • Urine retention
  • Erectile dysfunction
  • Diarrhoea
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11
Q

How is postural hypotension treated?

A

Flurocortisone

Midodrine

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12
Q

What are the side effects of flurocortisone?

A

Oedema

Hypertension

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13
Q

How does midodrine work and what are the side effects?

A

Alpha agonist

SE = Hypertension

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14
Q

How does gastroparesis present and how is it treated?

A
  • Presentation:
    • Nausea/vomiting
    • Early satiety
    • Post-prandial bloating
  • Treatment:
    • Anti-emetics
    • Erythromycin
    • Gastric pacing
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15
Q

How is the diarrhoea in autonomic neuropathy treated?

A

Codeine phosphate

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16
Q

What are the risk factors for Gestational diabetes?

A
  • Over 25 years old
  • Overweight
  • High BP
  • Family history
  • HIV +ve
  • Non-caucasian
  • Previous gestational DM
17
Q
A