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Prog > Diabetic Meds > Flashcards

Diabetic Meds Flashcards

1
Q

Metformin

A

decreases gluconeogenesis and increasing peripheral utilisation of glucose

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2
Q

Dapagliflozin

A

SGLT2 inhibitor

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3
Q

Empagliflozin

A

SGLT2 inhibitor

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3
Q

SGLT2 inhibitor action

A

Reversibly inhibits sodium-glucose co-transporter 2 in the renal proximal convoluted tubule and ↑urinary glucose excretion

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4
Q

SGLT2 inhibitor S/E

A

UTI, DKA

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5
Q

SGLT2 inhibitor indication

A

Preferred if heart failure or renal disease are predominant

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6
Q

Exenatide

A

GLP-1 receptor agonist

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7
Q

Liraglutide

A

GLP-1 receptor agonist

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8
Q

Dulaglutide

A

GLP-1 receptor agonist

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9
Q

GLP-1 receptor agonist indication

A

preferred if cerebrovascular disease is predominant

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10
Q

GLP-1 receptor agonist action

A

Bind to and activate the GLP-1 receptor to increase insulin secretion in the presence of raised glucose concentrations, suppress glycogen secretion and slow gastric emptying.

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11
Q

GLP-1 receptor agonist S/E

A

GI upset, Acute pancreatitis

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12
Q

Vildagliptin

A

DPP-4 inhibitor

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13
Q

Sitagliptin

A

DPP-4 inhibitor

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14
Q

Saxagliptin

A

DPP-4 inhibitor

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15
Q

DPP-4 inhibitor action

A

Increased levels of GLP-1 and GIP result in increased insulin synthesis and secretion from beta-cells and possibly reduced appetite

Prog (4 decks)

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