diabetic drugs Flashcards
1
Q
biguanide
A
metformin
enhances effect of insulin
SE: lactic acidosis
2
Q
Sulfonylureas
A
gliclizide
Increase insulin secretion from pan beta cells
SE: hypoglycaemia, weight gain
3
Q
Meglitinides
A
Nateglinade
hypo, weight gain
4
Q
DPP4-inhibitor
A
sitapliptin
inhibit GLP-1 breakdown
-> increase insulin secretion
SE: GI, pancreatitis
5
Q
GLP-1 agonists
A
exenatide
Stim GLP-1
SE: pancreatitis
6
Q
SGLT-2 inhibitor
A
daptogliflozin
increase glycosuria
SE: UTI
7
Q
alpha- glucosidase inhibitor
A
acrabose
reduce intestinal absorption
8
Q
Thiazolidinediones
A
Pioglitazone
reduce insulin resistance via stimulation for PPARs and
SE: WG, oedema, CF
9
Q
Amylin analogs
A
Pramlintide
reduce glucagon release, reduce gastric emptying, increase saciety
10
Q
IFG
A
6.1-7
11
Q
IGT
A
7.8-11.1