diabetic drugs Flashcards

1
Q

biguanide

A

metformin
enhances effect of insulin

SE: lactic acidosis

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2
Q

Sulfonylureas

A

gliclizide
Increase insulin secretion from pan beta cells

SE: hypoglycaemia, weight gain

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3
Q

Meglitinides

A

Nateglinade

hypo, weight gain

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4
Q

DPP4-inhibitor

A

sitapliptin
inhibit GLP-1 breakdown
-> increase insulin secretion

SE: GI, pancreatitis

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5
Q

GLP-1 agonists

A

exenatide
Stim GLP-1

SE: pancreatitis

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6
Q

SGLT-2 inhibitor

A

daptogliflozin
increase glycosuria

SE: UTI

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7
Q

alpha- glucosidase inhibitor

A

acrabose

reduce intestinal absorption

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8
Q

Thiazolidinediones

A

Pioglitazone

reduce insulin resistance via stimulation for PPARs and
SE: WG, oedema, CF

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9
Q

Amylin analogs

A

Pramlintide

reduce glucagon release, reduce gastric emptying, increase saciety

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10
Q

IFG

A

6.1-7

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11
Q

IGT

A

7.8-11.1

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