diabetic complications Flashcards
What are microvascular complications
neurology, nephropathy, retinopathy
Microvascular complications
CVD & stroke
Diabetic retinopathy
most common microvascular
only tight glycemic control can prevent this
other than this nothing can reverse it.
ACR - albumin createnin ratio to diagnose diabetic nephropahty
> 3 or more is clinically significant
treatment of nephropathy
Only if HTN
target 130/80. Has to be with an ace inhibitor.
Primary prevention of atorvastatin 20mg is recommended in patients with established CKD.
treatment of neuropathy
good glycemic control
- Amitriptyline, duloxetine, gabapentin, pergabalin.
capsaicin cream - localised.
Tramadol - short term.
Macrovascular
Endothelial dysfunction is central to the development of atherosclerosis and can be triggered by hyperlipidaemia, hypertension, hyperglycaemia and smoking.
Target BP in diabetes
140/90 unless target organ damage then 130/80
Ace inhibitor for everyone regardless of age
Then CCB then thiazide like diuretic.
When should patients be offered atorvastatin 20mg
if QRISK score >10%
Patients with T1DM should be offered atorvastatin 20mg if…
- They are >40 years
- They have had diabetes for > 10 years
- established nephropathy
- any cardiovascular risk factors.