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203- reproduction and endocrinology > diabetes type 2 > Flashcards

diabetes type 2 Flashcards

1
Q

In type 2 diabetes what is the islet characterised by?

A

A deficit in β-cells
Increased β-cell apoptosis,
Extracellular amyloid deposits derived from IAPP (amylin)

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2
Q

What are the causes of diabetes type 2?

A 
Genetic
maternal hyperglycaemia 
Intrauterine growth retardation -all lead to reduced beta cell mass 
Old age
Change in the gut  microbiota
Glucotoxicity & Lipotoxicity
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203- reproduction and endocrinology (6 decks)

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