Diabetes remission post bariatric surgery

Question 1

What is the prognosis for patients post-bariatric surgery regarding diabetes and obesity?

Answer 1

Excellent prognosis

Patients have favorable outcomes related to diabetes and obesity after surgery.

Question 2

What does the STAMPEDE trial compare?

Answer 2

Medical therapy with gastric bypass or sleeve gastrectomy

The STAMPEDE trial evaluates the effectiveness of surgical versus medical approaches.

Question 3

How is diabetes remission defined in the context of bariatric surgery?

Answer 3

HbA1c <7.0% without medications

This measure indicates effective management of diabetes post-surgery.

Question 4

What percentage of patients achieved HbA1c <7.0% without medications at 3 years?

Answer 4

58%

This statistic reflects the effectiveness of bariatric surgery in achieving diabetes remission.

Question 5

What are key factors for success in achieving diabetes remission after bariatric surgery?

Answer 5

• Diabetes duration <8 years
• Significant early weight loss

These factors contribute to higher remission rates post-surgery.

Question 6

What is the diabetes remission rate for Roux-en-Y gastric bypass at 3 years, unadjusted and adjusted?

Answer 6

• Unadjusted: 48%
• Adjusted: 42%

These rates indicate the effectiveness of this specific surgical procedure.

Question 7

What factors increase a patient’s chances of diabetes remission after bariatric surgery?

Answer 7

• No insulin use
• 5-year diabetes history

These factors are associated with better outcomes in diabetes management.

Question 8

What is the generally expected remission rate for patients post-bariatric surgery?

Answer 8

50%

This rate is based on various evidences regarding surgical outcomes.

Question 9

What were the diabetes remission rates for Roux-en-Y gastric bypass according to Mingrone et al.’s study?

Answer 9

• 37.5% at 5 years
• 25% at 10 years

This study provides long-term insights into remission rates following surgery.

Question 10

What is notable about the ARMMS-T2D study?

Answer 10

3-year interim results with 5-year results expected in 2023

This study is ongoing and will provide further data on diabetes management.

Question 11

What advantage did surgery show over medical therapy according to the STAMPEDE trial?

Answer 11

Superior quality of life

Surgical intervention led to improvements in patients’ overall well-being compared to medical therapy alone.

Question 12

What is the percentage reduction in the risk of microvascular complications per year of diabetes remission?

Answer 12

19%

This statistic highlights the health benefits of achieving diabetes remission.

Question 13

What HbA1c level indicates a significant reduction in microvascular complications?

Answer 13

HbA1c <6.5%

This level is associated with a lower risk of complications for patients.

Question 14

True or False: Less than 40% of patients achieve HbA1c <6.5% within the first year after surgery.

Answer 14

True

This indicates that while many achieve remission, fewer reach very stringent control early on.