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Endocrine > Diabetes pharm > Flashcards

Diabetes pharm Flashcards

1
Q

oral incretin mimetic

A

semaglutide

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2
Q

twice daily mimetics

A

exenatide

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3
Q

one daily mimetics

A

liraglutide, lixizenatide

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4
Q

once weekly mimetic

A

exenatide ER, Trulicity, ozempic

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5
Q

GLP-1 agonist MOA

A

enhances glucose dependent insulin secretion by the beta cells, suppresses glucagon secretion, slows gastric emptying, increases satiety

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6
Q

indication for incretin mimetics

A

monotherapy or adjunct therapy in patients taking metformin, SU, or TZD

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7
Q

3 day window for missed dose – glp agonist

A

exenatide ER, albigulutide, dulaglutide

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8
Q

5 day window for missed dose – glp agonist

A

5 day window for missed dose

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9
Q

rapid acting insulin types

A

insulin lispro, insulin aspart, insulin gluisine, inhaled human insulin

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10
Q

insulin lispro brand name

A

humalog

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11
Q

insulin lispro onset

A

15-30 minutes

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12
Q

insulin aspart brand name

A

novolog and fiasp

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13
Q

novolog onset

A

15-30 minutes

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14
Q

fiasp onset

A

5-20 minutes

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15
Q

insulin glulisine brand name

A

apidra

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16
Q

apidra onset

A

15-30 minutes

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17
Q

inhaled human insulin brand name

A

afrezza

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18
Q

afrezza onset

A

12-15 minutes

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19
Q

peak time for rapid-acting insulin

A

1-2 hours

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20
Q

duration for rapid acting insulin

A

3-5 hours

2.5-3 for afrezza

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21
Q

short acting insulin

A

regular insulin (U-100)

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22
Q

regular insulin brand name

A

Humulin R, Novolin R

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23
Q

onset for short acting

A

30-60 minutes

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24
Q

peak for short acting

A

2-3 hours

25
Q

duration for regular insulin

A

6-8 hours

26
Q

intermediate-acting insulin

A

NPH insulin, regular insulin (U-500)

27
Q

NPH insulin brand name

A

Humulin N, Novolin N

28
Q

NPH onset

A

2-4 hours

29
Q

NPH peak

A

4-6 hours

30
Q

NPH duration

A

8-12 hours

31
Q

regular insulin U-500 brand

A

Humulin R

32
Q

Humulin R onset

A

30-60 minutes

33
Q

Humulin R peak

A

2-3 hours

34
Q

Humulin R duration

A

15-24 hours

35
Q

long-acting insulin

A

insulin detemir, insulin glargine 100 and 300, insulin degludec

36
Q

long acting insulin peaks

A

relative flat peak

37
Q

insulin detemir brand

A

Levemir

38
Q

insulin detemir onset

A

2-4 hours

39
Q

insulin detemir duration

A

14-24 hours

40
Q

insulin glargine 100 brand

A

lantus

41
Q

lantus onset

A

2-4 hours

42
Q

lantus duration

A

22-24 hours

43
Q

insulin glargine 300 brand name

A

toujeo

44
Q

toujeo onset

A

6 hours

45
Q

toujeo duration

A

24-30

46
Q

insulin degludec brand

A

tresiba

47
Q

Tresiba onset

A

30-90 minutes

48
Q

Tresiba duration

A

42 hours

49
Q

Humulin 70/30

A

70% NPH and 30% regular insulin

50
Q

Novolin 70/30

A

70% NPH and 30% regular insulin

51
Q

Humalog 75/25

A

75% insulin lispro protamine suspension with 25% insulin lispro

52
Q

Humalog 50/50

A

50% insulin lispro protamine suspension with 50% insulin lispro

53
Q

NovoLog 70/30

A

70% insulin aspart protamine suspension with 30% insulin aspart

54
Q

lispro timing before food

A

0-15 minutes

55
Q

aspart timing before food

A

0-15 minutes

5 ac; 20 pc

56
Q

glulisine timing before food

A

0-15 min

57
Q

afrezza timing before food

A

0 min

58
Q

regular insulin 100 timing before food

A

30 min

59
Q

NPH mix

A

lispro, aspart, regular

Endocrine (7 decks)

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