Diabetes LEIK Flashcards

1
Q
  1. An 8-year-old boy with type 1 diabetes is being seen for a 3-day history of urinary
    frequency and nocturia. He denies flank pain and is afebrile. The urinalysis result is
    negative for blood and nitrites but is positive for a large amount of leukocytes and
    ketones. He has a trace amount of protein. Which of the following is the best test to
    order initially?
    A) Urine for culture and sensitivity
    B) 24-hour urine for protein and creatinine clearance
    C) 24-hour urine for microalbumin
    D) Intravenous pyelogram
A
  1. A) Urine for culture and sensitivity An 8-year-old male patient with the
    diagnosis of diabetes has a high risk of urinary tract infections (UTIs). A large
    amount of leukocytes in the urinalysis is abnormal, and he has been having
    symptoms of frequency and nocturia for the past 3 days. The urine culture would be
    ordered because he has a high risk of infection. The urine culture and sensitivity
    (C&S) is the best evaluation for diagnosing a UTI.
    1372
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2
Q
  1. A 73-year-old patient complains of recent episodes of acute-onset left-sided
    facial asymmetry, slurred speech, weakness, and dizziness, accompanied by
    weakness of the left arm and left leg. She reports that the episodes occur at random
    and last from 30 minutes to about 2 hours. Each episode resolved completely. The
    patient has type 2 diabetes with hyperlipidemia, peripheral arterial disease,
    hypertension, and osteoporosis. Her symptoms suggest:
    A) Benign paroxysmal positional vertigo
    B) Ménière’s disease
    C) Transient ischemic attack (TIA)
    D) Cerebrovascular accident (CVA)
A
  1. C) Transient ischemic attack (TIA) Transient ischemic attack (TIA) is a
    transient episode of ischemia in the brain, retina, or spinal cord without acute
    infarction. About 10% to 20% of patients with TIA will have a stroke within 90
    days. TIA signs and symptoms are acute onset of facial asymmetry, slurred speech,
    weakness, monocular visual loss, headache, and hemiplegia that resolves within
    minutes to several hours. TIA is a neurological emergency; should undergo brain
    imaging (MRI preferred) within 24 hours of onset.
    1405
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3
Q
  1. A 55-year-old woman who has had type 2 diabetes for 20 years is concerned about
    her kidneys. She has a history of three urinary tract infections (UTIs) within the past
    8 months, but is currently asymptomatic. Which of the following is the best course
    to follow?
    A) Recheck urine during the visit, send a urine specimen for culture and sensitivity,
    and refer to a nephrologist
    B) Order a urinalysis dipstick test to be repeated monthly
    C) Order a CT scan of the kidneys
    D) Provide empiric treatment for a UTI
A
  1. A) Recheck urine during the visit, send a urine specimen for culture and
    sensitivity, and refer to a nephrologist Although the patient is currently
    asymptomatic, her history of three urinary tract infections (UTIs) in 8 months
    warrants testing while she is in the office. A UTI is defined as the presence of
    100,000 organisms per milliliter of urine in asymptomatic patients or greater than
    100 organisms per milliliter of urine with pyuria (>7 WBCs/mL) in a symptomatic
    patient. Diabetic patients are at higher risk for UTIs and over time may develop
    bladder damage (cystopathy) and nephropathy. A nephrology consult is prudent.
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4
Q
  1. A 68-year-old woman with hypertension and diabetes is seen by the nurse
    practitioner for a dry cough that worsens at night when she lies in bed. She has
    shortness of breath, which worsens when she exerts herself, and has gained 6 lbs
    during the past 2 months. Her pulse rate is 90 beats/min and regular. She is on a
    nitroglycerine patch and furosemide daily. The best explanation for her symptoms is:
    A) Kidney failure
    B) Congestive heart failure
    C) ACE inhibitor-induced coughing
    D) Thyroid disease
    721
A
  1. B) Congestive heart failure In congestive heart failure (CHF), the heart’s
    ventricular function is inadequate. Symptoms include fatigue, diminished exercise
    capacity, shortness of breath, hemoptysis, cough, orthopnea, hypertension, nocturnal
    dyspnea, and edema. The kidneys begin to lose their normal ability to excrete
    sodium and water, leading to fluid retention. Lung congestion/pulmonary edema
    causes shortness of breath and a decreased ability to tolerate exercise.
    1446
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5
Q
  1. A 30-year-old woman with type 2 diabetes uses regular and NPH (neutral protein
    Hagedorn) insulin in the morning and in the evening. She denies changes in her diet
    or any illness, but recently started attending aerobic classes in the afternoon. Her
    fasting blood glucose level before breakfast is now elevated. Which of the following is
    best described?
    A) Somogyi phenomenon
    B) Dawn phenomenon
    C) Raynaud’s phenomenon
    D) Insulin resistance
A
  1. A) Somogyi phenomenon This is caused by too much insulin (or missing a meal
    or snack) in the evening, which results in hypoglycemia in the early morning (2 a.m.
    to 3 a.m.). The body compensates by secreting glucagon (from the liver) and
    epinephrine, which results in high blood glucose levels in the morning. The Somogyi
    phenomenon (or Somogyi effect) is also known as the rebound effect.
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6
Q
168. Which of the following would you recommend on an annual basis for an elderly
patient with type 2 diabetes?
A) Eye exam with an ophthalmologist
B) Follow-up visit with a urologist
C) Periodic visits to an optometrist
D) Colonoscopy
A
  1. A) Eye exam with an ophthalmologist Elderly patients with type 2 diabetes
    should have a dilated eye exam done annually by an ophthalmologist. They should
    also see a podiatrist once or twice a year. Preventive care also includes receiving a flu
    shot annually, receiving a Pneumovax vaccine if older than 60 years of age, and
    taking a 81-mg baby aspirin each day.
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7
Q
  1. A male patient has type 2 diabetes mellitus and a “sensitive stomach.” Which
    medication is least likely to cause him gastrointestinal distress?
    A) Naproxen sodium (Anaprox)
    B) Aspirin (Bayer’s aspirin)
    C) Erythromycin (E-mycin)
    D) Sucralfate (Carafate)
    786
A
  1. D) Sucralfate (Carafate) Naproxen sodium, aspirin, and erythromycin all have
    gastrointestinal side effects. Sucralfate is used to protect the stomach lining by
    building a protective layer over the stomach lining; it allows healing to occur.
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8
Q
203. An obese Asian patient with BMI (body mass index) of 33 complains of fatigue,
and excessive thirst and hunger. You suspect type 2 diabetes mellitus. Initial testing
to confirm diagnosis can include:
A) Fasting plasma glucose level
B) Glycated hemoglobin level (A1C)
C) Oral glucose tolerance testing
D) All of the above
794
A
  1. D) All of the above Type 2 diabetes mellitus screening tests include fasting
    plasma glucose level (>126 mg/dL), random plasma glucose level (>200 mg/dL), and
    oral glucose tolerance testing (2-hour blood glucose level >200 mg/dL) with a 75-g
    glucose load. Normal A1C levels are less than 6%.
    1519
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9
Q
218. Which chronic illness disproportionately affects the Hispanic population?
A) Diabetes mellitus
B) Hypertension
C) Alcohol abuse
D) Skin cancer
A
  1. A) Diabetes mellitus The risk of diabetes mellitus is two to three times higher in
    Mexican Americans than in non-Hispanic Americans.
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10
Q
  1. A 65-year-old Hispanic woman has a history of type 2 diabetes. A routine
    urinalysis reveals a few epithelial cells and is negative for leukocytes, nitrites, and
    protein. The serum creatinine is 1.5 mg/dL. Which of the following actions would
    you recommend next?
    A) Order a urine test for culture and sensitivity (C&S)
    B) Order a spot urine for microalbumin-to-creatinine ratio
    C) Because the urinalysis is negative, no further tests are necessary
    D) Recommend a screening intravenous pyelogram (IVP)
A
  1. B) Order a spot urine for microalbumin-to-creatinine ratio The American
    Diabetes Association (ADA) now prefers a spot urine for the microalbumin-tocreatinine
    ratio (ACR) test instead of a urine albumin test. Use the first morning
    void sample. The ACR has high predictive value for albuminuria and early kidney
    disease in patients with prediabetes, diabetes, and hypertension (McCulloch &
    Bakris, 2016). Because the patient has type 2 diabetes, both an annual urinalysis and
    an annual ACR test are recommended. Regarding the urinalysis result, a few
    epithelial cells is within normal limits.
    1559
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11
Q
  1. A 10-year-old boy has type 1 diabetes. His late afternoon blood sugars over the
    past 2 weeks have ranged between 210 mg/dL and 230 mg/dL. He currently
    injects 10 units of regular insulin and 25 units of NPH in the morning and 15 units
    of regular insulin and 10 units of NPH insulin in the evening. Which of the
    following is the best treatment plan for this patient?
    A) Increase both types of the morning dose
    B) Increase only the NPH insulin in the morning
    C) Decrease the afternoon dose of NPH insulin
    D) Decrease both NPH and regular insulin doses in the morning
A
  1. B) Increase only the NPH insulin in the morning Regular insulin is
    rapid/short-acting insulin. Depending on the type of regular insulin, the onset is 10
    to 15 minutes and peaks within an average of 1.5 hours, with a duration of 3 to 5
    hours. NPH insulin is an intermediate-acting insulin. Depending on the type of
    NPH insulin, the onset is 1.5 to 3 hours. NPH peaks in 4 to 12 hours, and the
    duration is from 18 to 24 hours. By increasing the morning NPH, the peak will
    occur in the afternoon, bringing down the blood glucose.
    1580
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12
Q
  1. A middle-aged patient newly diagnosed with type 2 diabetes wants to start an
    exercise program. All of the following statements are true except:
    A) If the patient is unable to eat due to illness, antidiabetic agents can be continued
    with frequent glucose monitoring
    B) Strenuous exercise is contraindicated for most patients with type 2 diabetes
    because of a higher risk of hypoglycemic episodes
    C) Exercise increases the body’s ability to metabolize glucose
    D) Patients who exercise vigorously in the afternoon may have hypoglycemic
    episodes in the evening or at night if they do not eat
A
  1. B) Strenuous exercise is contraindicated for most patients with type 2 diabetes
    because of a higher risk of hypoglycemic episodes Exercise is recommended
    because exercise helps to use the glucose stores and reduce blood sugar. When
    exercising, the patient should monitor blood sugar closely, especially if using insulin,
    to avoid hypoglycemia.
    1665
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13
Q
446. There is a higher risk of balanitis in which of the following conditions?
A) Renal insufficiency
B) Diabetes mellitus
C) Graves’ disease
D) Asthma
A
  1. B) Diabetes mellitus Balanitis is a yeast infection of the glans of the penis. Men
    who are not circumcised and who have diabetes mellitus are at higher risk for
    developing balanitis.
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14
Q
  1. All of the following patients should be screened for diabetes mellitus except:
    A) An obese man of Hispanic descent
    B) An overweight middle-aged Black woman whose mother has type 2 diabetes
    C) A woman who delivered an infant weighing 9.5 lbs
    D) A 30-year-old White man with hypertension
A
  1. D) A 30-year-old White man with hypertension

The 30-year-old White
man with hypertension would be the last patient to be screened for diabetes.
Not having any information about him also puts him lower on the list. Obesity,
ethnicity (Hispanic/Latino Americans, African Americans, Native Americans, Asian
Americans, Pacific Islanders, and Alaska natives), family history of diabetes, and
gestational diabetes (mother of the infant weighing 9.5 lbs) are all risk factors. These
were present in all of the other selections. Other risk factors for diabetes include
impaired glucose tolerance test, sedentary lifestyle, polycystic ovary syndrome
(PCOS), and hypertension.

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15
Q
576. Acanthosis nigricans is associated with all of the following disorders except:
A) Obesity
B) Diabetes
C) Colon cancer
D) Tinea versicolor
A
  1. D) Tinea versicolor Acanthosis nigricans is a benign skin condition that is a
    sign of insulin resistance. It appears as hyperpigmented velvety areas that are
    usually located on the neck and the axillae. It is rarely associated with some types of
    adenocarcinoma of the gastrointestinal tract. Tinea versicolor is a superficial infection
    of the skin (stratum corneum layer) that is caused by dermatophytes (fungi) of the
    tinea family. Another name for it is sunspots.
    1892
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16
Q
  1. Which of the following laboratory test results meet the diagnostic criteria for
    prediabetes?
    A) Fasting plasma glucose of 79 mg/dL
    B) A1C of 5.9%
    C) Random blood glucose of 200 mg/dL with polyuria, polydipsia, and polyphagia
    D) Random blood glucose of 200 mg/dL
A
  1. B) A1C of 5.9%

Do not confuse the criteria for diabetes with those for
prediabetes.

For prediabetes, look for an A1C between 5.7% to 6.4%, fasting plasma glucose (FPG) of 100 to 125 mg/dL, and/or 75-g oral glucose tolerance test (OGTT)
2-hour postprandial glucose of 140 to 199 mg/dL.

To diagnose diabetes, look for
random blood glucose ≥200 mg/dL with polyuria, polydipsia, and polyphagia, or
A1C ≥6.5%, FPG of ≥126 mg/dL, or 2-hour OGTT ≥200 mg/dL (American Diabetes Association, 2016).

17
Q
  1. A 55-year-old male patient with a body mass index (BMI) of 30 has a history of
    angina and type 2 diabetes. His lipid profile results are total cholesterol of 280
    mg/dL, low-density lipoprotein (LDL) of 195 mg/dL, and high-density lipoprotein
    (HDL) of 25 mg/dL. The nurse practitioner diagnoses him with hyperlipidemia and
    wants to start him on statin therapy. What intensity of treatment is recommended
    for this patient?
    A) Low-intensity statin
    B) Moderate-intensity statin
    C) High-intensity statin
    D) Very high-intensity statin
A
  1. C) High-intensity statin This patient fulfills the criteria for high-intensity
    statin dosing criteria from the 2013 American College of Cardiology/American
    Heart Association (ACC/AHA) blood cholesterol guideline. He already has heart
    disease (angina), type 2 diabetes, low-density lipoprotein (LDL) of 195 mg/dL, and
    low high-density lipoprotein (HDL) of 25 mg/dL. This patient is at very high risk
    for heart disease and warrants a high-intensity dose of statin. There are only two
    choices at this level: atorvastatin (Lipitor) 40 to 80 mg or rosuvastatin (Crestor) 20
    to 40 mg.
    2029