Diabetes Lecture (That sucked) Flashcards
Oral hypoglycemic drugs=
Sulfonylureas & Meglitinides
Oral anti-hyperglycemic drugs=
Biguanides, Thiazolidinediones, alpha-glucosidase inhibitor
Secreted by the beta-cells in the pancreas & plays major role in glucose homeostasis=
Insulin
After a meal, in response to increased plasma glucose levels form the intestinal absorption, there is a pulsatile increase in ______ secretion, which maintains euglycemia by facilitating peri[pheral glucose uptake in muscle and fat cells
Insulin
When blood glucose levels rise between meals, stimulation of what normally SUPPRESSES hepatic glucose production?
Insulin
Excess glucose prompts what?
Lipid synthesis
Decreases blood glucose, decreases blood fatty acids, decreases amino acids, increases protein synthesis, and increases fuel storage
Insulin secretion
Insulin deficiency & glucagon excess=
Type 1 Diabetes
Rapid Onset Insulin=
Insulin Lispro
Short-acting insulin=
Regular insulin
Causes cells to release stored food into the blood
Glucagon
Allows cells to take up glucose (and amino acids) from the blood
Insulin
Slows glucose absorption in duodenum and suppresses glucagon secretion
Amylin
Decreases GI activity; suppresses glucagon and insulin secretion
Somatostatin
Intermediate-acting insulin=
NPH (Humulin-N)