Diabetes Drugs Flashcards
1
Q
T1MD main drugs?
A
Insulin
2
Q
First line T2DM
A
Weight loss and diet
3
Q
Second line T2DM
A
Metformin
4
Q
What type of drug is metformin?
A
Biguanide
6
Q
Where does metformin act and what is the result?
A
Liver
Increases insulin sensitivity
Helps weight
7
Q
When is metformin contraindicated?
A
CKD
eGFF=/
8
Q
When should a second medication for goycaemic control be added to metformin?
A
When HbA1c = or > 53
9
Q
What are the side effects of metfromin?
A
Nausea
Diarrhoea
Abdo pain
(not hypoglycaemia)
10
Q
Third line T2DM
A
Sulfonylurea
11
Q
Name a sulfonylurea
A
Glicazide
12
Q
Where does a sulfonylurea act and what is the result?
A
Beta cells in pancreas
Increased insulin secretion
13
Q
What are the side effects of a sulfonylurea?
A
Hypoglycaemia Increased weight (as glucose driven into cell)
