Diabetes and Endocrinology

Question 1

What antibody is most likely to be elevated in Hashimoto’s thyroiditis?

Answer 1

anti-thyroid peroxidase (anti-TPO)

Question 2

What drug can typically cause worsening glucose control?

Answer 2

prednisolone

Question 3

Which medication is most likely to be effective in improving glycemic control and causing weight loss in a patient with type 2 diabetes mellitus and a BMI of 34?

Answer 3

semaglutide

Question 4

What are the effects of GLP-1 receptor agonists?

Answer 4

lower blood glucose levels and promote weight loss in patients with type 2 diabetes
stimulate insulin secretion, suppress glucagon release, slow gastric emptying, and increase satiety

Question 5

What is the first step in treating a diabetic ketoacidosis?

Answer 5

start intravenous 0.9% sodium chloride

Question 6

What is the second step in treatment of a DKA?

Answer 6

fixed rate insulin infusion
started after fluid therapy has been commenced